Results 221 to 230 of about 228,358 (272)

Macromolecular crowding sensing during osmotic stress in plants

Trends in Biochemical Sciences
Osmotic stress conditions occur at multiple stages of plant life. Changes in water availability caused by osmotic stress induce alterations in the mechanical properties of the plasma membrane, its interaction with the cell wall, and the concentration of ...
Cesar Cuevas-Velazquez   +2 more
exaly   +2 more sources

Comparison of Natural Polysaccharides and Synthetic Polymers in Facilitating Macromolecular Crowding to Create Customized Extracellular Matrix-Rich Supramolecular Assemblies from Fibroblasts.

open access: greenACS Applied Bio Materials
Regenerative medicine relies on tissue engineering to create functional tissue constructs that can repair or replace damaged organs. This process requires both structural support, such as physical scaffolds, cell adhesion sites, and spatial organization ...
Bitan Guchhait   +3 more
semanticscholar   +3 more sources

Macromolecular crowding effects on protein dynamics.

International Journal of Biological Macromolecules
Macromolecular crowding experiments bridge the gap between in-vivo and in-vitro studies by mimicking some of the cellular complexities like high viscosity and limited space, while still manageable for experiments and analysis.
Nilimesh Das   +4 more
semanticscholar   +3 more sources

Macromolecular Crowding by Polyethylene Glycol Reduces Protein Breathing.

Journal of Physical Chemistry Letters, 2023
Most efforts to understand macromolecular crowding focus on global (i.e., complete) unfolding, but smaller excursions, often called breathing, promote aggregation, which is associated with several diseases and the bane of pharmaceutical and commercial ...
I. Chu   +3 more
semanticscholar   +1 more source

Macromolecular crowding: obvious but underappreciated

Trends in Biochemical Sciences, 2001
Biological macromolecules evolve and function within intracellular environments that are crowded with other macromolecules. Crowding results in surprisingly large quantitative effects on both the rates and the equilibria of interactions involving macromolecules, but such interactions are commonly studied outside the cell in uncrowded buffers.
exaly   +3 more sources

Nonspecific interaction and overlap concentration influence macromolecular crowding effect on glucose oxidase activity.

International Journal of Biological Macromolecules, 2023
Macromolecular crowding can change kinetics of enzyme catalysis. How interaction between enzymes and neighboring macromolecules contributes to the crowding effect on enzyme catalysis has not been quantitatively revealed.
Siyuan Xu, Jie Wang, Jian Dong
semanticscholar   +1 more source

Macromolecular dynamics in crowded environments

The Journal of Chemical Physics, 2010
The structural and dynamical properties of macromolecules in confining or crowded environments are different from those in simple bulk liquids. In this paper, both the conformational and diffusional dynamics of globular polymers are studied in solutions containing fixed spherical obstacles.
Carlos, Echeverria, Raymond, Kapral
openaire   +2 more sources

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