Results 81 to 90 of about 16,667 (258)

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

Advanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu, Yao Yao, Yeongun Ko, Grant Grasman, Jeffery E. Raymond, Albert Chang, Yuxuan Deng, Grant Dominic, Michael Triebwasser, Joerg Lahann   +9 more
wiley   +1 more source

Crowding Induces Entropically-Driven Changes to DNA Dynamics That Depend on Crowder Structure and Ionic Conditions

Frontiers in Physics, 2018
Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection.
Warren M. Mardoum, Stephanie M. Gorczyca, Kathryn E. Regan, Tsai-Chin Wu, Rae M. Robertson-Anderson   +4 more
doaj   +1 more source

How does domain replacement affect fibril formation of the rabbit/human prion proteins. [PDF]

PLoS ONE, 2014
It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily form fibrils and is unlikely to cause prion diseases.
Xu Yan, Jun-Jie Huang, Zheng Zhou, Jie Chen, Yi Liang   +4 more
doaj   +1 more source

A coil-globule transition of a semiflexible polymer driven by the addition of spherical particles

, 1997
The phase behaviour of a single large semiflexible polymer immersed in a suspension of spherical particles is studied. All interactions are simple excluded volume interactions and the diameter of the spherical particles is an order of magnitude larger ...
A. D. Dinsmore, A. P. Minton, A. Vrij, A. Yu. Grosberg, A. Yu. Grosberg, A. Yu. Grosberg, A. Yu. Grosberg, A. Yu. Grosberg, C. Williams, D. Chandler, G. J. Vroege, H. N. W. Lekkerkerker, H. N. W. Lekkerkerker, H. Walter, I. M. Lifshitz, J. P. K. Doye, K. Merchant, K. Yoshikawa, L. D. Murphy, M. Dijkstra, M. Ueda, P. Bolhuis, P. G. Bolhuis, P. G. De Gennes, P. G. de Gennes, P. Grassberger, R. P. Sear, R. P. Sear, R. P. Sear, R. P. Sear, R. van Roij, Richard P. Sear, S.-T. Sun, U. Bastolla, W. C. K. Poon   +34 more
core   +1 more source

Macromolecular Crowding of Lipocalins

The FASEB Journal, 2007
Lipocalins are a family of proteins with a tertiary structure of a beta barrel core with alpha‐helices external to the barrel core and normally two disulfide bonds. The lipocalins are an important small molecule binding protein. The lipocalins can be very diverse in overall amino acid sequence (<40%sequence homology) just maintaining core amino ...
openaire   +1 more source

Multifunctional Oxadiazole‐Based Polycatenars: A Pathway to Polar Columnar Phases

Advanced Materials Interfaces, EarlyView.
Aromatic core fluorination directs oxadiazole‐based polycatenars into ferroelectric and antiferroelectric columnar phases with supergelation and photo‐responsiveness. ABSTRACT Polar columnar liquid crystals (LCs) offer a promising pathway to nanostructured architectures for next‐generation ferroelectric devices.
Yu Cao, Tejal Nirgude, Jonathan Jende, Alexander Jarosik, Alexey Eremin, Feng Liu, Masafumi Yoshio, Mohamed Alaasar   +7 more
wiley   +1 more source

Competition Between Liquid‐Liquid Crystalline Phase Separation (LLCPS) and Liquid‐Liquid Phase Separation (LLPS) in Amyloid Fibril Colloidal Systems

Advanced Science, EarlyView.
This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
wiley   +1 more source

Multifactorial bioengineering in the tendon context to maintain tenocyte phenotype and to direct dermal fibroblasts towards tenogenic lineage

Bioactive Materials
Considering that cells in vivo are simultaneously exposed to multiple signals, multifactorial bioengineering slowly but surely becomes the state of play in controlling cell function in vitro. In this context, herein we assessed the simultaneous effect of
Adrian Djalali-Cuevas, Mandy Rettel, Frank Stein, Mikhail Savitski, Ioannis Gkiatas, Anastasios Korompilias, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis   +10 more
doaj   +1 more source

The unfolding of iRFP713 in a crowded milieu [PDF]

PeerJ, 2019
The exploring of biological processes in vitro under conditions of macromolecular crowding is a way to achieve an understanding of how these processes occur in vivo.
Olesya V. Stepanenko, Olga V. Stepanenko, Irina M. Kuznetsova, Konstantin K. Turoverov   +3 more
doaj   +2 more sources