Results 101 to 110 of about 1,540,630 (392)

ACTIVATION OF CYTOTOXIC MACROPHAGE WITH MACROPHAGE

open access: yesThe KITAKANTO Medical Journal, 1978
Mouse peritoneal exudate macrophages induced by peptone (macrophages) were activated with a lymphokine, macrophage activating factor (MAF), and became cytotoxic against various tumor cells. Peritoneal resident adherent-cells from normal mice were not activated with MAF.When macrophages were incubated with aggregated human immunoglobulin G (agg-HGG) for
openaire   +3 more sources

Macrophage Heterogeneity [PDF]

open access: yesVox Sanguinis, 1979
Abstract. Macrophages are a mobile, functionally diverse group of cells which may be recruited and stimulated to a high degree of metabolic activity. Heterogeneity may be detected from one site to another and result from local influences, e.g. lung v.
K E, Hopper, P R, Wood, D S, Nelson
openaire   +2 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Hypoxia Induces Macrophage tnfa Expression via Cyclooxygenase and Prostaglandin E2 in vivo

open access: yesFrontiers in Immunology, 2019
Macrophage phenotypes are poorly characterized in disease systems in vivo. Appropriate macrophage activation requires complex coordination of local microenvironmental cues and cytokine signaling.
Amy Lewis, Philip M. Elks
doaj   +1 more source

Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]

open access: yes, 1975
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
A. V. Boand   +25 more
core   +1 more source

Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection.

open access: yesJCI Insight, 2019
Newly emerging viruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV), Middle Eastern respiratory syndrome CoVs (MERS-CoV), and H7N9, cause fatal acute lung injury (ALI) by driving hypercytokinemia and aggressive inflammation through ...
Li Liu   +18 more
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Origins and diversity of macrophages in health and disease

open access: yesClinical & Translational Immunology, 2020
Macrophages are the first immune cells in the developing embryo and have a central role in organ development, homeostasis, immunity and repair. Over the last century, our understanding of these cells has evolved from being thought of as simple phagocytic
Gopalkrishna Sreejit   +3 more
doaj   +1 more source

Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking. [PDF]

open access: yes, 2019
Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular interaction between numerous cell types including macrophages.
Cherqui, Stephanie   +4 more
core   +1 more source

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

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