Results 131 to 140 of about 1,549,373 (292)

Chitin Derived Small Molecule AVR-48 Reprograms the Resting Macrophages to an Intermediate Phenotype and Decrease Pseudomonas aeruginosa Mouse Lung Infection [PDF]

, 2022
Sumita Behera, Sujogya Kumar Panda, Michael Donkor, Eesha Acharya, Harlan P. Jones, Suchismita Acharya   +5 more
openalex   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Chemical Modulation of in Vivo Macrophage Function with Subpopulation-Specific Fluorescent Prodrug Conjugates

, 2017
Antonio Fernández, Matthieu Vermeren, Duncan C. Humphries, Ramon Subirós‐Funosas, Nicole D. Barth, Lara Campana, Alison C. MacKinnon, Yi Feng, Marc Vendrell   +8 more
openalex   +1 more source

Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages

, 2020
Zhaoyang Wang, Zi-Da Zhen, Dongying Fan, Cheng‐Feng Qin, Daishu Han, Hongning Zhou, Peigang Wang, Jing An   +7 more
openalex   +1 more source

Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages [PDF]

, 2017
Shigeyasu Tsuda, Masakazu Shinohara, Toshihiko Oshita, Manabu Nagao, Nobuaki Tanaka, Takeshige Mori, Tetsuya Hara, Yasuhiro Irino, Ryuji Toh, Tatsuro Ishida, Ken‐ichi Hirata   +10 more
openalex   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Mechanisms of the lipopolysaccharide‑induced inflammatory response in alveolar epithelial cell/macrophage co‑culture

, 2020
Jiansheng Li, Yanqin Qin, Yulong Chen, Peng Zhao, Xuefang Liu, Haoran Dong, Wanchun Zheng, Suxiang Feng, Xiaoning Mao, Congcong Li   +9 more
openalex   +2 more sources

Early Macrophage Infiltration and Sustained Inflammation in Kidneys From Deceased Donors Are Associated With Long-Term Renal Function [PDF]

, 2016
Elena Guillén‐Gómez, Iara daSilva, Irene Silva, Yolanda Arce, Carme Facundo, Elisabet Ars, Alberto Breda, Alberto Ortíz, L. Guirado, José Ballarín, Montserrat Díaz-Encarnación   +10 more
openalex   +1 more source

Protective and pathogenic functions of macrophage subsets

Nature reviews. Immunology, 2011
P. Murray, T. Wynn
semanticscholar   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source