Results 201 to 210 of about 793,649 (316)

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

Advanced Healthcare Materials, EarlyView.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario, Lorenzo Moroni, Carlos Mota   +2 more
wiley   +1 more source

Quantum dots as biocompatible small RNA nanocarriers modulating macrophage polarization to treat Asherman's syndrome. [PDF]

NPJ Regen Med
Won JE, Park M, Hong SH, Kim YS, Song H.
europepmc   +1 more source

An Intervertebral Disc (IVD) Regeneration Model Using Human Nucleus Pulposus Cells (iHNPCs) and Annulus Fibrosus Cells (iHAFCs)

Advanced Healthcare Materials, EarlyView.
This study investigates hTert‐immortalized human nucleus pulposus (iHNPCs) and annulus fibrosus (iHAFCs) cells for intervertebral disc (IVD) regeneration and spinal fusion models. A 3D‐printed citrate‐based scaffold loaded with BMP9‐stimulated iHAFCs and BMP2‐stimulated iHNPCs effectively promotes bone and cartilage formation, mimicking the IVD ...
Yi Zhu, Qing Liu, Chao Yu, Hui Zhang, Jiamin Zhong, Yonghui Wang, Ou Mei, Ethan Gerhard, Wulin You, Guowei Shen, Changqi Luo, Xingye Wu, Jingjing Li, Yi Shu, Ya Wen, Usman Zeb, Hue H. Luu, Michael J. Lee, Lewis L. Shi, Yang Bi, Jian Yang, Jiaming Fan, Russell R. Reid, Tong‐Chuan He, Liangyuan Wen   +24 more
wiley   +1 more source

Crosstalk between lipid metabolism and macrophages in atherosclerosis: therapeutic potential of natural products. [PDF]

Front Cardiovasc Med
Qian T, Guo D, Sun L, Chi M, Ma X, Jin J.   +5 more
europepmc   +1 more source

Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells

Advanced Healthcare Materials, EarlyView.
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng, Yu Qian, Xinxin Xiao, Fengdi Gao, Guoqiang Ren, Cristian Pablo Pennisi   +5 more
wiley   +1 more source

The Multifaceted Role of Macrophages in Biology and Diseases. [PDF]

Int J Mol Sci
Brancewicz J, Wójcik N, Sarnowska Z, Robak J, Król M.   +4 more
europepmc   +1 more source

CARs for macrophages [PDF]

Nature Medicine, 2020
openaire   +2 more sources

Viscoelastic HyA Hydrogel Promotes Recovery of Muscle Quality and Vascularization in a Murine Model of Delayed Rotator Cuff Repair

Advanced Healthcare Materials, EarlyView.
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff, Aboubacar Wague, Michael Davies, Anouk R. Killaars, Derek Ning, Steven Garcia, Anthony Nguyen, Prashant Nuthalapati, Mengyao Liu, Xuhui Liu, Brian T. Feeley, Kevin E. Healy   +11 more
wiley   +1 more source

Extracellular Vesicle-Associated miR-ERIA Exerts the Antiangiogenic Effect of Macrophages in Diabetic Wound Healing. [PDF]

Diabetes
Zeng T, Sun K, Mai L, Hong X, He X, Lin W, Chen S, Yan L.   +7 more
europepmc   +1 more source

Self‐Doped and Biodegradable Glycosaminoglycan‐PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC‐Derived Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
The electrical properties and performance of conductive hydrogels based on sulfated‐glycosaminoglycan‐PEDOT (poly 3,4‐ethylenedioxythiophene) brush copolymers is studied, showing that the higher sulfation degree of heparin confers hydrogels with the highest conductivity.
Daniel Hachim, Olivia Hernández‐Cruz, James E. J. Foote, Richard Wang, Matthew W. Delahaye, Daniel J. Stuckey, Zhiping Feng, Jonathan P. Wojciechowski, Luke C. B. Salter, Junliang Lin, Sian E. Harding, Molly M. Stevens   +11 more
wiley   +1 more source