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Activation of Murine Macrophages

Current Protocols in Immunology, 1994
AbstractMacrophages can act as potent effector cells of the immune response. Cytokine signals generated during an immune response activate macrophages in a complex cascade of events. Activated macrophages are qualitatively different from mature resident tissue macrophages and from immature inflammatory macrophages.
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Mycobacteria and macrophage activation

Research in Microbiology, 1990
Recent studies that challenged some older concepts have led to the following conclusions: 1) During an infection of mice with M. bovis, BCG macrophages are activated according to certain criteria, but the increase in their bactericidal or bacteriostatic activity is limited to a small number of bacteria species; 2) interferon-gamma can activate ...
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Macrophage Activation by Immunostimulatory DNA

2000
Macrophage/dendritic cells and B cells remain the only cell types where direct responses to CpG DNA are well established. The role of macrophages in vivo in DNA clearance and the potent cytokine induction in macrophages and dendritic cells places them in the central role in the in vivo response to foreign DNA.
Stacey, K. J.   +3 more
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Macrophage Activation Syndrome

Arthritis & Rheumatology
Macrophage activation syndrome (MAS) is a state of immune hyperactivation that can result in life‐threatening multisystem end‐organ dysfunction. Often termed a “cytokine storm,” MAS occurs among the rheumatic diseases most typically in Still's disease but also in systemic lupus erythematosus and Kawasaki disease.
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Macrophage activation in human brucellosis

Infection, 1973
This report deals with some ultrastructural and functional changes which were observed in human monocytes from peripheral blood in patients treated with Brucella vaccine during the remittance phase of an acute B. melitensis infection. Monocytes from these patients showed increased “in vitro” phagocytic and bactericidal activities and displayed ...
E, Magliulo   +4 more
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MAP kinase activation in macrophages

Journal of Leukocyte Biology, 2001
AbstractStimulation of macrophages by a variety of agents causes activation of mitogen-activated protein kinases (MAPKs). Activation of MAPKs by lipopolysaccharide involves CD14 and Toll receptors. Subsequent steps still remain to be explored. Tumor necrosis factor-α (TNF-α)-induced activation of MAPKs has been shown to involve the death domain ...
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Macrophage Activation Syndrome

Clinical Pediatrics, 2016
Courtney B, Crayne   +2 more
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Macrophage Activation Syndrome

International Journal of Surgical Pathology, 2013
Nidhi, Aggarwal, Rohit, Aggarwal
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