A mathematical model for smooth muscle cell phenotype switching in atherosclerotic plaque [PDF]
Smooth muscle cells (SMCs) play a fundamental role in the development of atherosclerotic plaques. SMCs may ingest lipids in a similar way to monocyte-derived macrophages (MDMs) in the plaque. This can stimulate SMCs to undergo a phenotypic switch towards a macrophage-like phenotype.
arxiv
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng+8 more
wiley +1 more source
Macrophage polarization induced by oxidized phospholipids
Alexandra Kadl, Norbert Leitinger
openalex +1 more source
Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang+16 more
wiley +1 more source
Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages inLeishmaniaInfection [PDF]
Marion M. Chan+2 more
openalex +1 more source
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao+4 more
wiley +1 more source
Defining the relationship between cathepsin B and esophageal adenocarcinoma: conjoint analysis of Mendelian randomization, transcriptome-wide association studies, and single-cell RNA sequencing data [PDF]
Background: Esophageal cancer poses a significant global health challenge, with the incidence of esophageal adenocarcinoma (EAC), a predominant subtype, increasing notably in Western countries. Cathepsins, a family of lysosomal proteolytic enzymes, have been implicated in the progression of various tumors.
arxiv
NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis
In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu+11 more
wiley +1 more source
Regulation of Macrophage Polarization and Wound Healing [PDF]
Christopher Ferrante+1 more
openalex +1 more source
Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley +1 more source