Results 11 to 20 of about 1,368,417 (273)
Frontiers in Cellular and Infection Microbiology, 2022 Animal models are essential to understanding COVID-19 pathophysiology and for preclinical assessment of drugs and other therapeutic or prophylactic interventions.
Valerio Laghi +10 more
doaj +1 more source
Effects of mesoporous SiO2-CaO nanospheres on the murine peritoneal macrophages -- Candida albicans interface [PDF]
Int Immunopharmacol International Immunopharmacology. 2021 Mar
20;94:107457, 2021 The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a central role in host defense and are responsible for in vivo nanoparticle trafficking.
arxiv +1 more source
Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]
Bull Math Biol 85, 37 (2023), 2022 Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv +1 more source
Immunity, 2014 Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the body. At sites of infection, macrophages encounter and engulf invading microbes. Accordingly, macrophages possess specialized effector functions to kill or coordinate the elimination of their prey.
Jordan V. Price, Russell E. Vance
openaire +3 more sources
Frontiers in Immunology, 2022 BackgroundBAFF production is increased in IBD patients. However, the specific role of BAFF in IBD is still uncovered. This study aimed to investigate the expression and function of BAFF in experimental colitis and the potential mechanisms.MethodsBAFF ...
Ying Zhang +6 more
doaj +1 more source
Segmentation based tracking of cells in 2D+time microscopy images of macrophages [PDF]
, 2023 The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse microscopy macrophage data.
arxiv +1 more source
PTEN inhibits AMPK to control collective migration
Nature Communications, 2022 Pten is a tumour suppressor gene that is associated with highly invasive cancers such as glioblastoma. Here the authors show that PTEN loss results in increased migratory behaviour, which can be countered by targeting AMPK activity.
Florent Peglion +9 more
doaj +1 more source
Placental Macrophages Following Maternal SARS-CoV-2 Infection in Relation to Placental Pathology
Frontiers in Virology, 2022 IntroductionIn December 2019, a novel coronavirus, SARS-CoV-2, was identified. Whilst pregnant women appear to be at risk of severe infection, pre-term birth, and stillbirth, it is unclear whether placental dysfunction is a consistent feature of maternal
Megan C. Sharps +6 more
doaj +1 more source
Gut Microbes, 2021 Human milk oligosaccharides (HMOs) and milk fat globule membrane (MFGM) are highly abundant in breast milk, and have been shown to exhibit potent immunomodulatory effects.
Cong Liu +9 more
doaj +1 more source
Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice
Frontiers in Immunology, 2021 Neutrophil cytosolic factor 1 (Ncf1) is a major genetic factor associated with autoimmune diseases and has been identified as a key player in autoimmune mediated inflammation.
Mengyao Li +13 more
doaj +1 more source