Results 11 to 20 of about 1,971,731 (404)

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain [PDF]

open access: yesNature Communications, 2020
Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Xiaobing Yu   +8 more
semanticscholar   +4 more sources

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes

open access: yeseLife, 2022
Nicotinamide adenine dinucleotide phosphate (NADPH) is the primary electron donor for reductive reactions that are essential for the biosynthesis of major cell components in all organisms.
Clarisse Leseigneur   +6 more
doaj   +1 more source

In silico prediction of protein-protein interactions in human macrophages [PDF]

open access: yesBMC Research Notes, 2001
Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions.
Oussema Souiai   +4 more
semanticscholar   +1 more source

Matrix Stiffening Enhances DNCB-Induced IL-6 Secretion in Keratinocytes Through Activation of ERK and PI3K/Akt Pathway

open access: yesFrontiers in Immunology, 2021
Matrix stiffness, a critical physical property of the cellular environment, is implicated in epidermal homeostasis. In particular, matrix stiffening during the pathological progression of skin diseases appears to contribute to cellular responses of ...
Hyewon Chung   +8 more
doaj   +1 more source

Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Animal models are essential to understanding COVID-19 pathophysiology and for preclinical assessment of drugs and other therapeutic or prophylactic interventions.
Valerio Laghi   +10 more
doaj   +1 more source

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

open access: yesNature reviews. Immunology, 2020
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease severity and death in ...
M. Merad, Jérôme C. Martin
semanticscholar   +1 more source

The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid. [PDF]

open access: yes, 2014
We previously defined macrophages harvested from the peritoneal cavity of nude mice with subcutaneous human pancreatic tumors as "tumor-educated-macrophages" (Edu) and macrophages harvested from mice without tumors as "naïve-macrophages" (Naïve), and ...
Bouvet, Michael   +17 more
core   +6 more sources

A User-Friendly Approach for Routine Histopathological and Morphometric Analysis of Skeletal Muscle Using CellProfiler Software

open access: yesDiagnostics, 2022
Adult skeletal muscle is capable of active and efficient differentiation in the event of injury in both physiological and pathological conditions, such as in Duchenne muscular dystrophy (DMD).
Valerio Laghi   +3 more
doaj   +1 more source

The Macrophage Paradox [PDF]

open access: yesImmunity, 2014
Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the body. At sites of infection, macrophages encounter and engulf invading microbes. Accordingly, macrophages possess specialized effector functions to kill or coordinate the elimination of their prey.
Jordan V. Price, Russell E. Vance
openaire   +3 more sources

The complex TIE between macrophages and angiogenesis [PDF]

open access: yes, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M.   +81 more
core   +2 more sources

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