Results 1 to 10 of about 1,262 (147)
Cells, 2022 In mammalian cells, SLC35A2 delivers UDP–galactose for galactosylation reactions that take place predominantly in the Golgi lumen. Mutations in the corresponding gene cause a subtype of a congenital disorder of glycosylation (SLC35A2-CDG).
Magdalena Kot +7 more
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Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome
Molecular Pharmaceutics, 2023 Madin-Darby canine kidney (MDCK) cells are widely used to study epithelial cell functionality. Their low endogenous drug transporter protein levels make them an amenable system to investigate transepithelial permeation and drug transporter protein activity after their transfection.
Matthew D. Harwood +11 more
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Induction of Epithelial-mesenchymal Transition in MDCK II Cells
Bio-Protocol, 2021 Epithelial-mesenchymal transition (EMT) is a reversible process of epithelial cell transdifferentiation into a mesenchymal cell, that enables initiation of cell migration.
Agnieszka Pastula, Richard Lundmark
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Proteoglycans in polarized epithelial Madin-Darby canine kidney cells [PDF]
Biochemical Journal, 1995 Madin-Darby canine kidney (MDCK) cells were cultured on polycarbonate filters to study the synthesis and sorting of proteoglycans in polarized epithelial cells. Two strains of MDCK cells were used. MDCK I cells resemble distal tubule epithelial cells, and MDCK II cells share some characteristics with proximal tubule cells.
K, Svennevig, K, Prydz, S O, Kolset
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MethodsX, 2020 CRISPR-Cas9 gene editing has made it possible to specifically edit genes in a myriad of target cells. Here, a method for isoform-specific editing and clonal selection in Madin-Darby canine kidney (MDCK) epithelial cells is described in detail.
James M. Readler +3 more
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Viruses, 2020 Cats are becoming more popular as household companions and pets, forming close relationships with humans. Although feline viral diseases can pose serious health hazards to pet cats, commercialized preventative vaccines are lacking.
Xiaona Wang +10 more
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Metabolomics profiling reveals differences in proliferation between tumorigenic and non-tumorigenic Madin-Darby canine kidney (MDCK) cells [PDF]
PeerJ, 2023 Background Madin-Darby canine kidney (MDCK) cells are a cellular matrix in the production of influenza vaccines. The proliferation rate of MDCK cells is one of the critical factors that determine the vaccine production cycle.
Na Sun +11 more
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Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells. [PDF]
The Journal of cell biology, 1987 To study the intracellular transport of newly synthesized sphingolipids in epithelial cells we have used a fluorescent ceramide analog, N-6[7-nitro-2,1,3-benzoxadiazol-4-yl] aminocaproyl sphingosine (C6-NBD-ceramide; Lipsky, N. G., and R. E. Pagano, 1983, Proc. Natl. Acad. Sci. USA, 80:2608-2612) as a probe. This ceramide was readily taken up by filter-
van Meer, G. +3 more
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Autophagy Reports, 2023 Epithelial cells transport substances through the cellular and paracellular pathways. The last one depends on tight junctions, particularly on claudins, the family of integral membrane proteins responsible for the permeability and selectivity of these ...
Jessica P. Campos-Blázquez +7 more
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Mechanisms involved in calcium oxalate endocytosis by Madin-Darby canine kidney cells
Brazilian Journal of Medical and Biological Research, 2000 Calcium oxalate (CaOx) crystals adhere to and are internalized by tubular renal cells and it seems that this interaction is related (positively or negatively) to the appearance of urinary calculi.
A.H. Campos, N. Schor
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