Results 231 to 240 of about 32,559 (283)

Effects of Shade and Concentrate Supplementation on Heat Tolerance, Metabolic, and Hematological Responses of Holstein Cows in a Semi‐Arid Environment

open access: yesNew Zealand Journal of Agricultural Research, Volume 69, Issue 3, June 2026.
This study evaluated heat tolerance and biochemical and haematological responses of Holstein cows exposed to different environmental conditions (full sun or shade) and feeding regimens (with or without concentrate) in the semi‐arid region of Brazil. Sixteen adult cows were distributed across four treatments.
David Ramos da Rocha   +11 more
wiley   +1 more source

Multi‐Omics and Machine Learning Integration Identifies Key Endothelial Modules in Carotid Artery Stenosis

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
This study integrates multi‐omics data (single‐cell RNA‐seq, bulk RNA‐seq, and proteomics) from carotid artery plaques to identify novel biomarkers for diagnosing stenosis. Through a computational pipeline involving cell population analysis, WGCNA, and machine learning models, we identified and validated NRP1 and XAF1 as key endothelial biomarkers ...
Jiayi Wu   +5 more
wiley   +1 more source

Counseling patients in the predictive genetics clinic for Huntington's disease: A qualitative analysis of ethnographic observations

open access: yesJournal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Little research has been conducted on patients' experiences inside the predictive genetics clinic. In this clinic, a person with a familial risk of inheriting a rare disease seeks a test that will provide them with information about their future health.
Shane Doheny   +5 more
wiley   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

open access: yesMedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li   +6 more
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Genome‐Wide DNA Methylation Changes Induced by High‐Fat Diet and Methyl Donor Supplementation in Female Lupus Models: An Exploratory Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
A high‐fat diet induces widespread DNA methylation changes in adipose tissue in lupus‐prone mice, while methyl‐donor supplementation (folic acid and vitamin B12) modulates inflammatory pathways, including IL‐17 signaling, in a diet‐dependent manner. ABSTRACT This exploratory study investigated the interactive effects of dietary fat content and methyl ...
Amanda Alves Ribeiro   +12 more
wiley   +1 more source

FLOWERING LOCUS T Genes MtFTb1 and MtFTb2 Act Redundantly to Promote Flowering Under Long Days in Medicago truncatula

open access: yesPlant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Flowering time is a crucial agronomic trait affecting yield and plant performance in different climates and photoperiods. While the molecular pathways regulating photoperiodic flowering are well‐characterized in Arabidopsis and cereals, they remain poorly understood in many other groups of plants.
Soledad Perez Santangelo   +1 more
wiley   +1 more source

Flexible Porous Pomelo Pith Derived Janus Liquid Metal and Adhesive Hydrogel Hybrid Electronic Skins

open access: yesSmart Medicine, Volume 5, Issue 3, June 2026.
We introduce a cost‐effective paradigm of LM‐derived e‐skin featuring anti‐freezing capability, efficient thermal management, and motion detection. The eco‐friendly porous pomelo pith (PP) is employed as the substrate for the patterning of LM and as the physical scaffold for adhesive hydrogels. ABSTRACT Liquid metal (LM)‐derived electronic skin (e‐skin)
Jinbo Li   +4 more
wiley   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro   +5 more
wiley   +1 more source

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