Results 91 to 100 of about 3,271,883 (209)

Transcriptome analysis of resistant soybean roots infected by Meloidogyne javanica

Genetics and Molecular Biology, 2012
Soybean is an important crop for Brazilian agribusiness. However, many factors can limit its production, especially root-knot nematode infection.
Maria Eugênia Lisei de Sá, Marcus José Conceição Lopes, Magnólia de Araújo Campos, Luciano Vilela Paiva, Regina Maria Amorim dos Santos, Magda Aparecida Beneventi, Alexandre Augusto Pereira Firmino, Maria Fátima Grossi de Sá   +7 more
doaj   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Prompt Sensitivity in AI Writing: A Methodological Caution for Corpus‐Based Analysis of AI‐Generated Language

The Modern Language Journal, EarlyView.
ABSTRACT Recent corpus‐based studies suggest generative AI systems such as ChatGPT can approximate human patterns of interpersonal metadiscourse in argumentative writing. These conclusions are typically based on AI‐generated texts produced using a single prompt, despite AI output being highly sensitive to even minor changes in prompt specification ...
Peter Crosthwaite, Shuyi (Amelia) Sun, Feng (Kevin) Jiang   +2 more
wiley   +1 more source

Genome-Wide Identification and Characterization of the ALOG Domain Genes in Rice

International Journal of Genomics, 2019
The ALOG domain genes, named after the Arabidopsis LSH1 and Oryza G1 (ALOG) proteins, have frequently been reported as key developmental regulators in rice and Arabidopsis. However, the investigation of the ALOG gene family is limited. Here, we conducted
Na Li, Yang Wang, Jing Lu, Chuan Liu
doaj   +1 more source

Jasmonate biosynthesis regulates key events in barley vegetative and reproductive development

New Phytologist, EarlyView.
Generation and general phenotypes of hvaoc mutants. Summary Cereal grain is a global food staple. Filial tissues in grain, such as the embryo and endosperm, grow embedded in the maternal ovule and surrounding ovary wall. Maternal tissues provide nutrition and protection but are progressively reduced and degraded as filial tissues expand, driving grain ...
Jian Luo, Linsan Liu, Xiujuan Yang, Olivia Doolan, Tanicha Duangta, Emily Lyon, Jonathan Griffin, Jennifer Shoesmith, Wenhao Wu, Ruth Hamilton, Mirjam Nuter, Mikah Katay‐Fodor, Neil Bricklebank, Nicola Aberdein, Guoping Zhang, Colin Turnbull, Matthew R. Tucker, Sarah M. McKim   +17 more
wiley   +1 more source

Identification, Classification of the MIKC-Type MADS-Box Gene Family, and Expression Analysis of Female and Male Flower Buds in Walnut (Juglans regia, Juglandaceae)

Horticulturae
MIKC-type MADS-box transcription factors constitute one of the largest gene families in plants, playing pivotal roles in regulating plant growth and development, hormone signaling transduction, and responses to biotic and abiotic stresses. However, there
Caihua Guo, Olumide Phillip Fesobi, Zhongrong Zhang, Xing Yuan, Haochang Zhao, Shaowen Quan, Jianxin Niu   +6 more
doaj   +1 more source

Phytoplasma effector SAP54 hijacks plant reproduction by degrading MADS-box proteins and promotes insect colonization in a RAD23-dependent manner.

PLoS Biology, 2014
Pathogens that rely upon multiple hosts to complete their life cycles often modify behavior and development of these hosts to coerce them into improving pathogen fitness. However, few studies describe mechanisms underlying host coercion.
Allyson M MacLean, Zigmunds Orlovskis, Krissana Kowitwanich, Anna M Zdziarska, Gerco C Angenent, Richard G H Immink, Saskia A Hogenhout   +6 more
doaj   +1 more source

Floral bilateral symmetry: one axis, many details

New Phytologist, EarlyView.
Dorsal petal morphological diversity among monkeyflower species. Summary Symmetry is a major component of floral diversity. Most flowers are radially or bilaterally symmetric, with bilateral symmetry (monosymmetry) having evolved repeatedly from radial ancestors. Since the identification of the dorsal identity gene CYCLOIDEA (CYC) in snapdragon, floral
Ya Min
wiley   +1 more source

Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2 [PDF]

, 2009
PERIOD proteins are central components of the Drosophila and mammalian circadian clocks. The crystal structure of a Drosophila PERIOD (dPER) fragment comprising two PER-ARNT-SIM (PAS) domains (PAS-A and PAS-B) and two additional C-terminal alpha-helices (
Strauss, Holger M, Wolf, Eva, Schulze, Sabrina, Sven Hennig, Arens, J., Hennig, Sven; id_orcid, Yildiz, O., Strauss, Holger M., Holger M Strauss, Julia Arens, Kramer, Achim, Arens, Julia, Sabrina Schulze, Schulze, S., Eva Wolf, Vanselow, Katja, Yildiz, Özkan, Katja Vanselow, Strauss, H., Hennig, S., Kramer, A., Vanselow, K., Wolf, E., Strauss, H. M., Achim Kramer, Ozkan Yildiz, Hennig, Sven   +26 more
core   +1 more source