Results 121 to 130 of about 3,271,883 (209)

Data‐driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour, Allison M. Neltner, Mitchell A. Klusty, Cole Corbett, Angelique D. Gonzalez, David A. Gutman, David W. Fardo, Adam D. Bachstetter, Cody Bumgardner, Margaret E. Flanagan, Peter T. Nelson   +10 more
wiley   +1 more source

MADS interactomics : towards understanding the molecular mechanisms of plant MADS-domain transcription factor function

, 2013
Protein-protein and protein-DNA interactions are essential for the molecular action of transcription factors. By combinatorial binding to target gene promoters, transcription factors are able to up- or down-regulate the expression of these genes.
Smaczniak, C.D.
core  

Expression profiling and transcriptional regulation of the SRS transcription factor gene family of common bean (Phaseolus vulgaris) in symbiosis with Rhizobium etli.

PLoS ONE
The SRS/STY transcription factors from the model legumes: Lotus japonicus and Medicago truncatula, are part of regulatory networks that play relevant roles for nodule development during the N-fixing symbiosis with rhizobia.
Litzy Ayra, Gladys Jiménez-Nopala, Gabriela Guerrero, Sara Isabel Fuentes, Alfonso Leija, Mario Ramírez, Georgina Hernández   +6 more
doaj   +1 more source

Additional file 13: of Comparative analysis of binding patterns of MADS-domain proteins in Arabidopsis thaliana

, 2018
Figure S7. Central enrichment of G-boxes and TCP class I and II. Kernel density plot showing positions in peak centers relative to the peak summit of matches to the G-box (CACGTG) and the motifs for TCP class I (GGNCCCAC) and class II (GGGNCC(A/G)C) in (A) AG; (B) AP1; (C) AP3; (D) FLC; (E) PI; (F) SEP3; (G) SOC1 and (H) SVP. (PDF 232 kb)
Aerts, Niels, de Bruijn, Suzanne, van Mourik, Hilda, Angenent, Gerco, van Dijk, Aalt   +4 more
openaire   +1 more source

A Wild Emmer Wheat B3 Transcription Factor Regulates Seed Growth and Nutrient Allocation

Plant, Cell &Environment, Volume 49, Issue 11, Page 7900-7910, November 2026.
ABSTRACT Seed weight (SW) and nutrient allocation are key determinants of yield and grain quality in wheat, yet the regulatory basis of naturally occurring variation in these traits remains poorly resolved. Wild emmer wheat (Triticum dicoccoides), the progenitor of modern wheat, retains extensive eco‐geographically structured genetic diversity that was
Davinder Sharma, Zechariah Haber, Manas R. Prusty, Raz Avni, Mijal Perez, Moshe Ronen, Rakesh Kumar, Arava Shatil‐Cohen, Paz Haboub, Chen Omer, Gilor Kelly, Hadar Aviv, Adi Doron‐Faigenboim, Din Moshe, Weronika Jasinska, Leah Rosental, Eitan Millet, Hanan Sela, Or Sperling, Amir Sharon, Anna Mintz Dub, Yariv Brotman, Nir Sade   +22 more
wiley   +1 more source

Additional file 9: of Comparative analysis of binding patterns of MADS-domain proteins in Arabidopsis thaliana

, 2018
Table S6. Co-occurrence of several CArG-box variants in ChIP-seq peaks. (A) Amount of peaks with a single occurrence and with multiple occurrences of pre-defined CArG-box variants. (B) Amount of peaks that contain only CC(A/T)6GG, only CC(A/T)7G or both motifs. (C) Amount of peaks that contain only CC(A/T)7G, only C(A/T)8G or both motifs. (D) Amount of
Aerts, Niels, de Bruijn, Suzanne, van Mourik, Hilda, Angenent, Gerco, van Dijk, Aalt   +4 more
openaire   +1 more source

USP25 stabilises GLI1 through K48‐linked deubiquitination within a reciprocal regulatory circuit in osteoarthritis models

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
GLI1‐centred USP25‐GLI1 reciprocal regulation in OA‐relevant models. Hedgehog/GLI1 signalling transcriptionally reinforces USP25 expression, while USP25 deubiquitinates and stabilises GLI1. This reciprocal circuit is associated with inflammatory and cartilage‐catabolic changes in the tested models.
Qian Zhang, Yinyan Ye, Yijie Huang, Jun Li, Dongfeng Huang   +4 more
wiley   +1 more source

The Biology and Biochemistry of PhoH2 proteins [PDF]

, 2013
PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core  

Additional file 6: of Comparative analysis of binding patterns of MADS-domain proteins in Arabidopsis thaliana

, 2018
Table S5. Unique and overlapping peak centers in each dataset. A peak center is defined as the region 250 bp upstream and downstream of a peak summit. (PDF 52 kb)
Aerts, Niels, de Bruijn, Suzanne, van Mourik, Hilda, Angenent, Gerco, van Dijk, Aalt   +4 more
openaire   +1 more source

Consensus‐Defined Sarcopenic Obesity and a Related Dynapenic Obesity Phenotype in Relation to Early Cognitive Impairment

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Previous studies examining sarcopenic obesity in relation to cognitive function have utilized heterogeneous operational definitions. Some studies have evaluated low muscle strength combined with obesity, more appropriately described as dynapenic obesity, under the broader term sarcopenic obesity.
Mu‐Cyun Wang, Tao‐Chun Peng, Jeng‐Min Chiou, Yen‐Ching Chen, Jen‐Hau Chen   +4 more
wiley   +1 more source