Results 51 to 60 of about 764,832 (295)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
El maestro rural en Colombia: desafíos ante la memoria y la reconstrucción del tejido social
Praxis & Saber, 2022 En muchas zonas rurales de Colombia, el maestro es la única presencia estatal. Por ello, adquiere un rol importante para el liderazgo comunitario, en virtud del lugar histórico de la escuela rural en los territorios donde el conflicto armado dejó ...
William Orozco
doaj
El filósofo: hombre, héroe, maestro
Análisis, 2018 Podría considerarse que la filosofía con el pasar de los siglos se ha alejado paulatinamente de las realidades de su tiempo para dedicarse a conceptualizar; pero la filosofía, como otras ciencias están llamadas a pensar, discurrir y –sobretodo- resolver
Andrés Escobar Vásquez
doaj +1 more source
Backscattering Between Helical Edge States via Dynamic Nuclear Polarization
, 2012 We show that that the non-equilibrium spin polarization of one dimensional helical edge states at the boundary of a two dimensional topological insulator can dynamically induce a polarization of nuclei via the hyperfine interaction.
Adrian Del Maestro +3 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Bio-grafía, 2010 Los maestros de las Instituciones Educativas de la Ciudad de Medellín, encuentran en la Red de Cualificación e Investigación de Maestros de Ciencias Naturales y Educación Ambiental de la Escuela del Maestro, Secretaría de Educación de Medellín, un ...
Diana Gallego Madrid +2 more
doaj
Theory of liquid film growth and wetting instabilities on graphene
, 2018 We investigate wetting phenomena near graphene within the Dzyaloshinskii-Lifshitz-Pitaevskii theory for light gases composed of hydrogen, helium and nitrogen in three different geometries where graphene is either affixed to an insulating substrate ...
Del Maestro, Adrian +3 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source