Results 101 to 110 of about 6,213 (261)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
José Manuel Blecua, "Maestro de maestros"
Tropelías: Revista de Teoría de la Literatura y Literatura Comparada, 2009 José Manuel Blecua, "Maestro de maestros"
openaire +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
La práctica pedagógica del maestro de las escuelas normales de Manizales: 1982-1994
Revista Latinoamericana de Estudios Educativos, 2009 El artículo expone cómo las prácticas pedagógicas de los maestros de las dos Escuelas Normales de Manizales, han dependido, a través de las dos últimas décadas de la segunda mitad del siglo XX, del cumplimiento de directrices legislativas ...
Yheny Lorena Pineda Rodríguez +1 more
doaj
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Los maestros republicanos: Legislación y conflictividad profesional (1931-1936)
Historia de la Educación, 2013 La Segunda República española aportó novedades y mejoras importantes para los maestros de primaria, pero también suscitó resistencias y conflictos profesionales que hasta ahora apenas se habían evidenciado.
Antonio MOLERO PINTADO
doaj
Absolute quantification of cerebral tissue oxygen saturation with multidistance broadband NIRS in newborn brain. [PDF]
Biomed Opt Express, 2021 Kovacsova Z +4 more
europepmc +1 more source