Results 81 to 90 of about 101,022 (282)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

How conceive knowledge of different subjects polyvalent French teachers of first grade?

open access: yesRevista MENDIVE, 2004
This article offers a look about how a French Institute related problems versatility in basic education are addressed.
Odile Espinosa
doaj  

Historia escolar cotidiana: una categoría analítica intermedia para comprender las prácticas de enseñar historia en primaria

open access: yesAnuario Mexicano de Historia de la Educación
Al referirnos a la enseñanza de la historia a menudo se habla de una enseñanza memorística de fechas, batallas y personajes importantes, y del dictado, la copia y la memorización pasiva de textos. Una fuente de tales aseveraciones han sido los programas
Rocío Ramírez González
doaj   +1 more source

La Educación y el Aporte de las Normales en Nariño

open access: yesEstudios Latinoamericanos, 2015
Las normales en Nariño han cumplido un gran papel en cuanto a la formación de los futuros maestros, quienes a través de la práctica pedagógica han formado los cimientos de una educación que ha contribuido con el seguimiento en valores de las nuevas ...
José Oliden Muñoz Bravo
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Intelligent Assistant with Artificial Intelligence for Language Learning

open access: yesApplied Sciences
An intelligent assistant with artificial intelligence (AI) for language learning was developed. A dynamic user interface and a supervised feedback module using web technologies (HTML5, CSS3, and JavaScript ES6+) and Python v3.9 for supporting language ...
Diego De-La-Cruz-Salcedo   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The free will of indifference at a particular physical world

open access: yesRevista MENDIVE, 2004
This article has the objective of promoting the different theses about the theory of the free way and sustains one of them, the one related with the fact that all that exists is well determined by a net of multiple and varied causes.
Miguel Espinosa
doaj  

Los maestros del colegio del arte mayor de la seda de Valencia en una fase de crecimiento manufacturero (1686-1755)

open access: yesHispania, 2014
El presente trabajo se basa en el estudio de los 2.077 nuevos maestros que ingresaron en el colegio del arte mayor de la seda de Valencia entre 1686 y 1755, y revela la complejidad de la evolución que experimentó la corporación. El repliegue en favor del
Ricardo Franch Benavent
doaj   +1 more source

Maestro

open access: yes, 2015
Centro de Investigación en Lectura y Escritura (CILE)
openaire   +3 more sources

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