Results 41 to 50 of about 29,084 (308)

La evaluación de las ciencias sociales en la educación secundaria. tensiones entre discursos y prácticas

open access: yesEducación, Formación e Investigación, 2016
El Proyecto se origina en el diálogo entre docentes del Instituto Superior de Formación Docente (ISFD) de la Escuela Normal Superior ―Maestros Argentinos‖.
Silvia Fabiana Luchessi   +4 more
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Aproximaciones a los modos de construcción del saber didáctico para abordar la alfabetización inicial

open access: yesEducación, Formación e Investigación, 2015
La presente investigación interpretó los modos en que los docentes construyen su saber didáctico para abordar la alfabetización inicial (AI). La muestra estuvo constituida por los docentes de primero y segundo grado de escuelas públicas de Corral de ...
Silvia Fabiana Luchessi   +3 more
doaj  

Inclusive pedagogy and active learning in higher education: Cluster and dimensional insights into teaching competency integration

open access: yesSocial Sciences and Humanities Open
This study examines the interrelationship between inclusive teaching competencies and the implementation of active learning methodologies in Peruvian higher education, addressing critical gaps in faculty development and pedagogical equity within resource-
María Luisa Medina Vásquez   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

La imagen del maestro español, entre el miedo y la parodia (1876-1931)

open access: yesEl Futuro del Pasado, 2022
Las imágenes que representan al maestro y el aula escolar han desempeñado un papel fundamental en el desarrollo de los sistemas educativos. Este artículo constituye una búsqueda del origen iconográfico de las representaciones que tuvieron una utilización
Ignacio Gil-Díez Usandizaga
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

El primer monumento a la educación: Benemérita Escuela Nacional de Maestros

open access: yesDebates por la Historia
En este trabajo se plantea un análisis histórico que contribuya en el conocimiento y divulgación de la última etapa de construcción de la Benemérita Escuela Nacional de Maestros, una de las instituciones educativas más importantes de México en materia ...
Raquel Díaz Galván
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

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