Results 101 to 110 of about 11,492 (193)
Macrophage-derived exosomal miR-155 regulating hepatocyte pyroptosis in MAFLD
Background: Previous studies have shown that pyroptosis in hepatocyte is essential for the development of MAFLD. Growing evidence has shown that exosomal miRNAs-mediated communication between inflammatory cells and hepatocyte is an important link in ...
Xiang Wang +4 more
core +1 more source
Based on meta‐analyses and cumulative epidemiological evidence, the present study identifies 11 genetic variants in 11 genes that are truly associated with the risk of hepatocellular carcinoma. Our work presents a systematic synopsis, which helps elucidate the mechanisms of carcinogenesis and provides insights into the early diagnosis and novel ...
Yujin Shi +17 more
wiley +1 more source
[Non-alcoholic steatohepatitis - from NAFLD to MAFLD]
Non-alcoholic steatohepatitis (NASH) as one entity of non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and accompanies the rise in the prevalence of obesity, diabetes mellitus, hypertension and hyperlipidemia ...
Jean-François Dufour +3 more
core +1 more source
This study conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) to investigate whether acupuncture treatment is more beneficial than Western medicine treatment for patients with nonalcoholic fatty liver disease. The results showed that acupuncture was significantly superior to Western medicine in terms of clinical ...
Bin Yu +8 more
wiley +1 more source
open-Background: attualmente, nella popolazione occidentale, obesità e steato-epatite associata a disfunzione metabolica sono altamente prevalenti (MAFLD).
GIACOMONI, RUGGERO
core
This cross‐sectional study of 84 general practices found 24.3% had At‐Risk MASH defined by FNI > 0.30, and 4.3% had advanced fibrosis defined by FIB‐4 > 2.67. Diabetes and socio‐economic disadvantage were strong predictors of significant liver disease.
Leon A. Adams +7 more
wiley +1 more source
Genome-wide association studies have identified several genetic variants associated with nonalcoholic fatty liver disease. To emphasize metabolic abnormalities in fatty liver, metabolic (dysfunction)-associated fatty liver disease (MAFLD) has been ...
Young Lee +7 more
doaj +1 more source
Prevalence of Obesity and Related Conditions and GLP‐1 Use in Medicare Fee‐for‐Service Beneficiaries
ABSTRACT Aims This study estimated the number and percentage of Medicare fee‐for‐service (FFS) beneficiaries who use GLP‐1 RAs, are currently eligible or could become eligible if ongoing‐trial indications receive approval and coverage. Materials and Methods This retrospective cohort study used Medicare enrolment and claims data, representing 100% of ...
Sonia Kim +3 more
wiley +1 more source
Associations between skeletal muscle strength and chronic kidney disease in patients with MASLD
Background A skeletal muscle strength (SMS) decline is associated with metabolic diseases, but whether SMS also declines with chronic kidney disease (CKD) in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD) is uncertain ...
Xin-Lei Zhang +14 more
doaj +1 more source
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek +1 more
wiley +1 more source

