Results 61 to 70 of about 11,492 (193)

Dietary Soybean vs. Palm Oils Differ in Effects on Liver Fat in Adults With MAFLD: A 16‐Week, Double‐Masked, Randomized Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Dietary linoleic acid (LA)‐rich oils reduce liver fat in healthy adults who are not otherwise undergoing weight loss strategies. Effects on the liver fat in adults with fatty liver disease are unknown. Objective The objective of this randomized double‐masked controlled trial was to compare the effects of a dietary soybean oil (SO ...
Martha A. Belury, Rachel M. Cole, Ai Ni, Arunark Kolipaka, Manjunathan Nanjappa, Kristin Thompson, Ali Kalhori, Stephan Zarich, Rolando E. Choriego, Rafael Jimenez‐Flores, Na Li   +10 more
wiley   +1 more source

The Protective Effect of Bilirubin on MAFLD May Be Mediated by Improving Insulin Re-Sistance and Alleviating Chronic Inflammation [PDF]

Mengying Yang,1,* Jing Liu,1,* Xiaoman Liu,1 Qianqian Li,1 Jun Liu,2 Baogui Wang1 1Department of Infectious Disease, Fuyang People’s Hospital, Fuyang, Anhui, People’s Republic of China; 2Physical Examination Center, Fuyang People’s Hospital ...
Liu X, Liu J, Wang B, Yang M, Li Q
core  

Global burden of MAFLD, MAFLD related cirrhosis and MASH related liver cancer from 1990 to 2021

Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease globally, driven by rising obesity, metabolic syndrome (MetS), and type 2 diabetes mellitus (T2DM).
Qingjuan Wu, Dongjie Wu, Ziang Yao, Wenliang Lv, Ziwei Guo, Runhan Mao   +5 more
core   +1 more source

Comparisons of MAFLD, healthy, and NAFLD groups.

, 2022
Comparisons of MAFLD, healthy, and NAFLD groups.
Takafumi Sasada (14165041), Shinsaku Fukuda (4169743), Shigeyuki Nakaji (501233), Hirotake Sakuraba (12859288), Kenichiro Mikami (14165047), Satoshi Sato (1826323), Tatsuya Mikami (5054954), Shogo Kawaguchi (2556919), Chikara Iino (4169746), Tetsuyuki Tateda (14165038), Kaori Sawada (53781), Go Igarashi (14165044), Tetsu Endo (14165050)   +12 more
core   +1 more source

Circulating MicroRNA Profiling for Phenotypic Stratification in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease: A Candidate-Based Study

Current Issues in Molecular Biology
Metabolic dysfunction-associated fatty liver disease (MAFLD) comprises phenotypic subgroups, including type-2 diabetes-associated MAFLD (T2D-MAFLD), obesity-associated MAFLD (OB-MAFLD), and lean MAFLD (L-MAFLD).
Sumbal Nida, Dilshad Ahmed Khan, Muhammad Amjad Pervez, Nayyar Chaudhry, Mohammad Qaiser Alam Khan, Alveena Younas   +5 more
doaj   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

MAFLD as part of systemic metabolic dysregulation

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. In recent years, a new terminology and definition of metabolic dysfunction-associated fatty liver disease (MAFLD) has been proposed.
Gao, Xin, Zheng, Ming-Hua, Byrne, Christopher D, Zhao, Jing, Cao, Ying-Ying, Byrne, Chris, Targher, Giovanni, Sun, Dan-Qin, Liu, Lu   +8 more
core   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Plant-derived bioactive peptides and protein hydrolysates for managing MAFLD: A systematic review of in vivo effects

Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a growing health concern worldwide. Among the pursuit of therapeutic interventions, interest in natural bioactive compounds has intensified because of their potential ...
Santos-Sánchez, Guillermo, Cruz-Chamorro, Iván   +1 more
core   +1 more source

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

MedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao, Zhaoling Li, Lianxin Zhang, Yitong Xu, Ziwei Wang, Zixun Wang, Aiden Xian, Liwen Zheng, Jingxuan Chen, Yufei Han, Chunhua Shan, Kaikai Lu, Ming Tao, Ling Zhang, Weiguang Zhang, Wei Huang, Yuhui Wang, Rui Wei, Erdan Dong, Xunde Xian   +19 more
wiley   +1 more source