Results 131 to 140 of about 3,186 (156)

Dual Role of the Spinal Endocannabinoid System in Response to Noxious Stimuli: Antinociceptive Pathways and Neuropathic Pain Mechanisms. [PDF]

Int J Mol Sci
Saldaña R, Carrascosa AJ, Torregrosa AB, Navarrete F, García-Gutiérrez MS, Manzanares J.   +5 more
europepmc   +1 more source

The endocannabinoidome-gut microbiome-brain axis as a novel therapeutic target for autism spectrum disorder. [PDF]

J Biomed Sci
Campanale A, Siniscalco D, Di Marzo V.
europepmc   +1 more source

Investigation of the Efficacy and Mechanism of Monoacylglycerol Lipase Inhibitors in Diabetic Foot Ulcers. [PDF]

Pharmaceuticals (Basel)
Liang Z, Wang Y, Li M, Li H, Han Y, Zhao Y, Yang J, Tan Y, Dai G, Guo N, Yao J, Lu X, Zhang G.   +12 more
europepmc   +1 more source

Upregulation of GLT-1 Expression Attenuates Neuronal Apoptosis and Cognitive Dysfunction via Inhibiting the CB1-CREB Signaling Pathway in Mice with Traumatic Brain Injury. [PDF]

Biomolecules
Bu B, Ma R, Wang C, Jiang S, Xu X.
europepmc   +1 more source

Morpholine as a privileged scaffold for neurodegenerative disease therapeutics. [PDF]

RSC Adv
Parmbil SK, Kumar S, Rangarajan TM, Grace Thomas Parambi D, Maliyakkal N, Petzer A, Petzer JP, Mathew B.   +7 more
europepmc   +1 more source

<i>Cannabis sativa</i> Root Extract Exerts Anti-Nociceptive and Anti-Inflammatory Effects via Endocannabinoid Pathway Modulation In Vivo and In Vitro. [PDF]

Int J Mol Sci
Jang SY, Jin HL, Yu GR, Lim DW, Park WH.
europepmc   +1 more source

Lipid droplet accumulation in microglia and their potential roles. [PDF]

Lipids Health Dis
Li Y, Zhao Q, Wang Y, Du W, Yang R, Wu J, Li Y.   +6 more
europepmc   +1 more source

Exploration of (R)-[¹¹C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates. [PDF]

Eur J Nucl Med Mol Imaging
He Y, Zheng M, Gu J, Reichert L, Trimborn J, Zhang H, Keller C, Crosby M, Collin L, Heer D, Pavlovic A, Topp A, Wittwer MB, Grether U, Gobbi L, Schibli R, Huang Y, Mu L.   +17 more
europepmc   +1 more source

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MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop

International Journal of Pharmaceutics, 2022
The ocular endocannabinoid system (ECS) including enzymes and CB1/CB2 receptors determines various substantial effects, such as anti-inflammatory activity and reduction of the intraocular pressure (IOP). The modulation of 2-arachidonoylglycerol (2-AG) levels obtained via MAGL inhibition is considered as a promising pharmacological strategy to activate ...
Patrizia Chetoni, Susi Burgalassi, Erica Zucchetti, Carlotta Granchi, Filippo Minutolo, Silvia Tampucci, Daniela Monti   +6 more
openaire   +2 more sources