Results 71 to 80 of about 6,305,091 (339)
RTF2 controls replication repriming and ribonucleotide excision at the replisome
Nature CommunicationsDNA replication through a challenging genomic landscape is coordinated by the replisome, which must adjust to local conditions to provide appropriate replication speed and respond to lesions that hinder its progression.
Brooke A. Conti +10 more
doaj +1 more source
Complexity, 2021 GIS (gas-insulated switchgear) is important equipment in the substation system in a complex microgrid network. Due to the long-term service in harsh operation environments, the electrical performance of GIS equipment will be seriously affected. Therefore,
Yu Yan +4 more
doaj +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Rail Track Maintenance Planning: An Assessment Model [PDF]
, 2000 In Australia, railway track maintenance costs comprise between 25-35 percent of total freight train operating costs. Track maintenance planning models have been shown to reduce maintenance costs by 5 to 10 percent though improved planning.
Ferreira, Luis +2 more
core +2 more sources
Fault diagnosis method for rotor system of centrifugal compressor units
You-qi chuyun, 2023 The rotor system of the centrifugal compressor unit comprises the rotor and the support structure. The change in the rotor balance state and the abnormal stiffness of the composite spring are common faults of the rotor system.
LIU Baoxia, WANG Meng, MA Yulei
doaj +1 more source
EMBO Journal, 1991 We describe a dominant behavioral marker, rol‐6(su‐1006), and an efficient microinjection procedure which facilitate the recovery of Caenorhabditis elegans transformants. We use these tools to study the mechanism of C.elegans DNA transformation.
C. Mello +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Research on Evaluation Index of High Temperature Performance of Rubberized Asphalt Binder
Frontiers in Materials, 2022 The high-temperature rheological properties of rubberized asphalt and mixture were evaluated by frequency scanning, repeated creep recovery (RCR) test, temperature sweep test, Hamburg wheel tracking test (HWTT).
Cheng Xie +5 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source