Results 11 to 20 of about 1,556 (163)
Toxicity Characterisation of Gambierdiscus Species from the Canary Islands [PDF]
Toxins, 2020 In the last decade, several outbreaks of ciguatera fish poisoning (CFP) have been reported in the Canary Islands (central northeast Atlantic Ocean), confirming ciguatera as an emerging alimentary risk in this region.
Araceli E. Rossignoli +5 more
doaj +3 more sources
Synthesis of C-Oligosaccharides through Versatile C(sp3 )-H Glycosylation of Glycosides. [PDF]
Angew Chem Int Ed Engl, 2022 The palladium‐catalyzed C(sp3)−H glycosylation of glycosides is disclosed. This saccharide assembly by C(sp3)−H glycosylation featured excellent site‐ and stereoselectivity and enabled the efficient synthesis of diverse C‐disaccharides and C‐trisaccharides.
Wu J, Kopp A, Ackermann L.
europepmc +2 more sources
The Formosalides: Structure Determination by Total Synthesis
Angewandte Chemie, Volume 133, Issue 1, Page 450-458, January 4, 2021., 2021 Total synthesis allowed the identification of the most likely stereostructure of the cytotoxic marine macrolides of the formosalide family (see structure) from eight possibilities. The successful route was based upon an inherently flexible blueprint that builds all stereogenic centers by strictly catalyst controlled transformations prior to formation ...
Saskia Schulthoff +5 more
wiley +2 more sources
Blockade of maitotoxin-induced oncotic cell death reveals zeiosis [PDF]
BMC Physiology, 2002 Maitotoxin (MTX) initiates cell death by sequentially activating 1) Ca2+ influx via non-selective cation channels, 2) uptake of vital dyes via formation of large pores, and 3) release of lactate dehydrogenase, an indication of cell lysis. MTX also causes formation of membrane blebs, which dramatically dilate during the cytolysis phase. To determine the
Mark Estacion, William P Schilling
core +4 more sources
The Journal of Physiology, Volume 601, Issue 14, Page 2935-2958, 15 July 2023., 2023 Abstract figure legend Amphipathic weak bases like CatSper blockers (B) diffuse across the sperm plasma membrane from a region of high concentration to one of low concentration (1). Inside the cell, these compounds are accumulated and protonated (BH+) into the acrosomal lumen (2).
Enrique I. Oliver +3 more
wiley +1 more source
Maitotoxin: An Inspiration for Synthesis [PDF]
Israel Journal of Chemistry, 2011 AbstractMaitotoxin holds a special place in the annals of natural products chemistry as the largest and most toxic secondary metabolite known to date. Its fascinating, ladder‐like, polyether molecular structure and diverse spectrum of biological activities elicited keen interest from chemists and biologists, who recognized its uniqueness and potential ...
K C, Nicolaou, Robert J, Aversa
openaire +2 more sources
Phytobioactive compounds as therapeutic agents for human diseases: A review
Food Science &Nutrition, Volume 11, Issue 6, Page 2500-2529, June 2023., 2023 Phytobioactive compounds are plant secondary metabolites and have remarkable therapeutic potential. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti‐inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic ...
Muhammad Riaz +10 more
wiley +1 more source
New insights into maitotoxin action [PDF]
European Journal of Biochemistry, 1988 Maitotoxin (3 ng/mol) induced a massive uptake of 45Ca2+ into BC3H1 cells. This effect exhibits a lag phase of 3 min. Inositol diphosphate formation occurred concomittantly with the 45Ca2+ uptake but inositol monophosphate formation was found only after a 5‐min delay following toxin addition.
F, Sladeczek +7 more
openaire +2 more sources
Health benefits of microalgae and their microbiomes
Microbial Biotechnology, Volume 15, Issue 7, Page 1966-1983, July 2022., 2022 Microalgae may offer solutions to the societal challenge we face concerning the lack of antibiotics treating the growing level of antimicrobial resistant bacteria and fungi in clinical and industrial settings. While the vast majority of microalgae and their associated microbiota are unstudied, they may be a fascinating and rewarding source for novel ...
Ines Krohn +8 more
wiley +1 more source
Synthese von C‐Oligosacchariden via vielseitiger C(sp3)‐H‐Glykosylierung von Glykosiden
Angewandte Chemie, Volume 134, Issue 11, March 7, 2022., 2022 Die Palladium‐katalysierte C(sp3)‐H‐Glykosylierung von Glykosiden wird erschlossen. Diese Saccharid‐Assemblierungsstrategie durch die C(sp3)‐H‐Glykosylierung zeichnet sich durch eine ausgezeichnete Site‐ und Stereoselektivität aus und ermöglicht die effiziente Synthese verschiedener C‐Disacchariden und C‐Trisacchariden.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley +1 more source