Results 11 to 20 of about 242,210 (352)
MHC class I allele diversity in cynomolgus macaques of Vietnamese origin [PDF]
PeerJ, 2019 Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important experimental animal models for carrying out biomedical researches. The results of biomedical experiments strongly depend on the immunogenetic background of animals, especially on
Shuting Huang +4 more
doaj +2 more sources
Major Histocompatibility Complex-B haplotype and ovarian graft response
Poultry Science, 2023 : Gonadal tissue transfer is considered one of the best methods to preserve genetic variability. Poultry hosts can receive a gonad from a donor of a different genetic background, sustain the growth of this graft, and produce gametes from it ...
Chi Cuong Quach +5 more
doaj +1 more source
Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]
, 1994 Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold +45 more
core +1 more source
Impact of Antigen Presentation Mechanisms on Immune Response in Autoimmune Hepatitis
Frontiers in Immunology, 2022 The liver is a very tolerogenic organ. It is continually exposed to a multitude of antigens and is able to promote an effective immune response against pathogens and simultaneously immune tolerance against self-antigens. In spite of strong peripheral and
Rossella Fasano +10 more
doaj +1 more source
Cholesterol lowering drug may influence cellular immune response by altering MHC II function[S]
Journal of Lipid Research, 2013 Major histocompatibility complex class II (MHC II) expressed on the surface of antigen-presenting cells (APCs) displays peptides to CD4+ T cells. Depletion of membrane cholesterol from APCs by methyl β-cyclodextrin treatment compromises peptide-MHC II ...
Koushik Roy +4 more
doaj +1 more source
Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation
Frontiers in Veterinary Science, 2022 Activation of human immune T-cells by swine leukocyte antigens class I (SLA-I) and class II (SLA-II) leads to xenograft destruction. Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the ...
Kaixiang Xu +43 more
doaj +1 more source
Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males [PDF]
, 2013 Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus
Alcaide M +8 more
core +1 more source
Downregulation of major histocompatibility complex class I in bovine papillomas [PDF]
, 2004 Bovine papillomavirus (BPV) induces papillomas in cattle; in the great majority of cases, these regress due to the host immune response, but they can persist and progress to malignancy.
Araibi, E.H. +3 more
core +1 more source
The major histocompatibility complex of reindeer
Rangifer, 1990 The major histocompatibility complex (MHC) is a system of closely linked genes showing an extremely high degree of polymorphism. These genes are major elements in the government of specific immune reactions.
I. Olsaker, K. H. Røed
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Arterial bypass and interposition grafts are used routinely across multiple surgical subspecialties. Current options include both autologous and synthetic materials; however, each graft presents specific limitations.
John P. Maufort +12 more
doaj +3 more sources