Results 31 to 40 of about 102,809 (247)

Endogenous versus exogenous fatty acid availability affects lysosomal acidity and MHC class II expression

Journal of Lipid Research, 2006
Although the immune system, inflammation, and cellular metabolism are linked to diseases associated with dyslipidemias, the mechanism(s) remain unclear.
S.C. Schweitzer, A.M. Reding, H.M. Patton, T.P. Sullivan, C.E. Stubbs, E. Villalobos-Menuey, S.A. Huber, M.K. Newell   +7 more
doaj   +1 more source

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]

, 1992
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Allen, Babbit, Bjorkman, Buus, Chen, Cramer, Del Val, DeLisi, Falk, Fauchère, Garrett, Jorgensen, Kidera, Kourilsky, Krug, Lambert, Lambert, Lambert, Margalit, Maryanski, Owen, Reddehase, Reddehase, Reddehase, Rötzschke, Saper, Schwartz, Serrano, Sette, Tirado-Rives, Townsend, Townsend, Townsend, Unanue, Van Bleek, Weiner, Wendoloski, Wold, Zinkernagel   +38 more
core   +1 more source

Evolution of major histocompatibility complex gene copy number.

PLoS Computational Biology, 2019
MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show remarkable copy-number variation both between and within species.
Piotr Bentkowski, Jacek Radwan
doaj   +1 more source

Major histocompatibility complex genomic investigation of endangered Chinese alligator provides insights into the evolution of tetrapod major histocompatibility complex and survival of critically bottlenecked species

Frontiers in Ecology and Evolution, 2022
BackgroundThe major histocompatibility complex (MHC) gene family, a vital immune gene family in vertebrates, helps animals defend against pathogens. The polymorphism of MHC genes is important for a species and is considered to be caused by the numerous ...
Ke He, Ke He, Ying Zhu, Ying Zhu, Shang-Chen Yang, Qing Ye, Qing Ye, Sheng-Guo Fang, Qiu-Hong Wan   +8 more
doaj   +1 more source

Major histocompatibility complex haplotype diversity in Arab horses from Argentina [PDF]

, 2017
La diversidad de los genes del complejo principal de histocompatibilidad (MHC) es clave en su función en la presentación de antígenos en el sistema inmune.
Carino, Mónica Herminia, Corbi Botto, Claudia Malena, Diaz, Silvina, Peral Garcia, Pilar, Sadaba, Sebastian Andres, Villegas Castagnasso, Egle Etel, Zappa, María Eugenia   +6 more
core   +3 more sources

Major histocompatibility complex: history of discovery, evolution, structure, significance in transplantation of allogeneic hematopoietic stem cells

Трансплантология (Москва), 2023
Aim. To reveal the significance of the major histocompatibility complex and the human leukocyte antigen evolutionary divergence in transplantation of allogeneic hematopoietic stem cells.
F. A. Omarova, M. Yu. Drokov, E. G. Khamaganova   +2 more
doaj   +1 more source

Non-classical immunology. Meeting Report [PDF]

, 2001
This large annual immunology meeting covered a wide range of subjects from biochemical protein characterizations to cell biology and the study of complex disease pathologies.
Allen, RL
core   +1 more source

Skeletal muscle major histocompatibility complex class I and II expression differences in adult and juvenile dermatomyositis

Clinics, 2012
OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria)
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +3 more
doaj   +1 more source

Growth of donor-derived dendritic cells from the bone marrow of murine liver auograft recipients in response to granulocyte/macrophage colony-stimulating factor [PDF]

, 1995
Allografts of the liver, which has a comparatively heavy leukocyte content compared with other vascularized organs, are accepted permanently across major histocompatibility complex barriers in many murine strain combinations without immunosuppressive ...
Fu, F, Fung, JJ, Lu, L, McCaslin, D, Qian, S, Rao, AS, Rudert, WA, Starzl, TE, Thomson, AW, Trucco, M   +9 more
core   +1 more source

The Marine Mammal Class II Major Histocompatibility Complex Organization

Frontiers in Immunology, 2019
Sirenians share with cetaceans and pinnipeds several convergent traits selected for the aquatic lifestyle. Living in water poses new challenges not only for locomotion and feeding but also for combating new pathogens, which may render the immune system ...
André Luiz Alves de Sá, André Luiz Alves de Sá, Breanna Breaux, Tibério Cesar Tortola Burlamaqui, Thaddeus Charles Deiss, Leonardo Sena, Michael Frederick Criscitiello, Maria Paula Cruz Schneider   +7 more
doaj   +1 more source