Results 11 to 20 of about 102,809 (247)

EBV lytic proteins BZLF1 and BILF1 inhibit the expression of major histocompatibility complex in Raji cells [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate whether BZLF1 and BILF1 can inhibit the expression of major histocompatibility complex(MHC)molecules in Raji cells during Epstein-Barr virus (EBV) lytic cycle.
ZHENG Hongling, GUO Qingwei, ZHANG Wei, ZHANG Yan, HE Xingbo, YE Bing
doaj   +1 more source

Major histocompatibility complex Class II-based therapy for stroke

open access: yesBrain Circulation, 2021
This review discusses the potential of major histocompatibility complex (MHC) Class II constructs as stroke therapeutics. We focus on the delivery of MHC Class II construct, DRmQ, as a safe and effective treatment for ischemic stroke.
Bella M Gonzales-Portillo   +4 more
doaj   +1 more source

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis

open access: yeseLife, 2023
Oligodendrocytes and their progenitors upregulate MHC pathways in response to inflammation, but the frequency of this phenotypic change is unknown and the features of these immune oligodendroglia are poorly defined.
Em P Harrington   +8 more
doaj   +1 more source

MergeReference: A Tool for Merging Reference Panels for HLA Imputation [PDF]

open access: yesGenomics & Informatics, 2017
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers.
Seungho Cook, Buhm Han
doaj   +1 more source

MHC class I allele diversity in cynomolgus macaques of Vietnamese origin [PDF]

open access: yesPeerJ, 2019
Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important experimental animal models for carrying out biomedical researches. The results of biomedical experiments strongly depend on the immunogenetic background of animals, especially on
Shuting Huang   +4 more
doaj   +2 more sources

Major Histocompatibility Complex-B haplotype and ovarian graft response

open access: yesPoultry Science, 2023
: Gonadal tissue transfer is considered one of the best methods to preserve genetic variability. Poultry hosts can receive a gonad from a donor of a different genetic background, sustain the growth of this graft, and produce gametes from it ...
Chi Cuong Quach   +5 more
doaj   +1 more source

Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]

open access: yes, 1994
Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold   +45 more
core   +1 more source

A Nonpolymorphic Class I Gene in the Murine Major Histocompatibility Complex [PDF]

open access: yes, 1984
DNA sequence analysis of a class I gene (QlO), which maps to the Qa2,3 locus in the C57BL/lO (H- 2b haplotype) mouse, reveals that it is almost identical to a cDNA clone (pH16) isolated from a SWR/J (H-2q haplotype) mouse liver cDNA library.
Flavell, Richard A.   +4 more
core   +1 more source

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]

open access: yes, 2014
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair   +3 more
core   +6 more sources

Cholesterol lowering drug may influence cellular immune response by altering MHC II function[S]

open access: yesJournal of Lipid Research, 2013
Major histocompatibility complex class II (MHC II) expressed on the surface of antigen-presenting cells (APCs) displays peptides to CD4+ T cells. Depletion of membrane cholesterol from APCs by methyl β-cyclodextrin treatment compromises peptide-MHC II ...
Koushik Roy   +4 more
doaj   +1 more source

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