EBV lytic proteins BZLF1 and BILF1 inhibit the expression of major histocompatibility complex in Raji cells [PDF]
Objective To investigate whether BZLF1 and BILF1 can inhibit the expression of major histocompatibility complex(MHC)molecules in Raji cells during Epstein-Barr virus (EBV) lytic cycle.
ZHENG Hongling, GUO Qingwei, ZHANG Wei, ZHANG Yan, HE Xingbo, YE Bing
doaj +1 more source
Major histocompatibility complex Class II-based therapy for stroke
This review discusses the potential of major histocompatibility complex (MHC) Class II constructs as stroke therapeutics. We focus on the delivery of MHC Class II construct, DRmQ, as a safe and effective treatment for ischemic stroke.
Bella M Gonzales-Portillo +4 more
doaj +1 more source
Oligodendrocytes and their progenitors upregulate MHC pathways in response to inflammation, but the frequency of this phenotypic change is unknown and the features of these immune oligodendroglia are poorly defined.
Em P Harrington +8 more
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MergeReference: A Tool for Merging Reference Panels for HLA Imputation [PDF]
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers.
Seungho Cook, Buhm Han
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MHC class I allele diversity in cynomolgus macaques of Vietnamese origin [PDF]
Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important experimental animal models for carrying out biomedical researches. The results of biomedical experiments strongly depend on the immunogenetic background of animals, especially on
Shuting Huang +4 more
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Major Histocompatibility Complex-B haplotype and ovarian graft response
: Gonadal tissue transfer is considered one of the best methods to preserve genetic variability. Poultry hosts can receive a gonad from a donor of a different genetic background, sustain the growth of this graft, and produce gametes from it ...
Chi Cuong Quach +5 more
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Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]
Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold +45 more
core +1 more source
A Nonpolymorphic Class I Gene in the Murine Major Histocompatibility Complex [PDF]
DNA sequence analysis of a class I gene (QlO), which maps to the Qa2,3 locus in the C57BL/lO (H- 2b haplotype) mouse, reveals that it is almost identical to a cDNA clone (pH16) isolated from a SWR/J (H-2q haplotype) mouse liver cDNA library.
Flavell, Richard A. +4 more
core +1 more source
Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair +3 more
core +6 more sources
Cholesterol lowering drug may influence cellular immune response by altering MHC II function[S]
Major histocompatibility complex class II (MHC II) expressed on the surface of antigen-presenting cells (APCs) displays peptides to CD4+ T cells. Depletion of membrane cholesterol from APCs by methyl β-cyclodextrin treatment compromises peptide-MHC II ...
Koushik Roy +4 more
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