Results 11 to 20 of about 9,502,784 (300)

MHC class I allele diversity in cynomolgus macaques of Vietnamese origin [PDF]

open access: yesPeerJ, 2019
Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important experimental animal models for carrying out biomedical researches. The results of biomedical experiments strongly depend on the immunogenetic background of animals, especially on
Shuting Huang   +4 more
doaj   +2 more sources

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

open access: yes, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves   +54 more
core   +1 more source

Major Histocompatibility Complex-B haplotype and ovarian graft response

open access: yesPoultry Science, 2023
: Gonadal tissue transfer is considered one of the best methods to preserve genetic variability. Poultry hosts can receive a gonad from a donor of a different genetic background, sustain the growth of this graft, and produce gametes from it ...
Chi Cuong Quach   +5 more
doaj   +1 more source

Downregulation of major histocompatibility complex class I in bovine papillomas [PDF]

open access: yes, 2004
Bovine papillomavirus (BPV) induces papillomas in cattle; in the great majority of cases, these regress due to the host immune response, but they can persist and progress to malignancy.
Marchetti, B   +6 more
core   +1 more source

Cholesterol lowering drug may influence cellular immune response by altering MHC II function[S]

open access: yesJournal of Lipid Research, 2013
Major histocompatibility complex class II (MHC II) expressed on the surface of antigen-presenting cells (APCs) displays peptides to CD4+ T cells. Depletion of membrane cholesterol from APCs by methyl β-cyclodextrin treatment compromises peptide-MHC II ...
Koushik Roy   +4 more
doaj   +1 more source

Impact of Antigen Presentation Mechanisms on Immune Response in Autoimmune Hepatitis

open access: yesFrontiers in Immunology, 2022
The liver is a very tolerogenic organ. It is continually exposed to a multitude of antigens and is able to promote an effective immune response against pathogens and simultaneously immune tolerance against self-antigens. In spite of strong peripheral and
Rossella Fasano   +10 more
doaj   +1 more source

Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment [PDF]

open access: yes, 1992
Selective expression of murine cytomegalovirus (MCMV) immediate-early (IE) genes leads to the presentation by the major histocompatibility complex (MHC) class I molecule L a of a peptide derived from MCMV IE protein pp89 (Reddehase, M. J., J.
Koszinowski, Ulrich H.   +13 more
core   +1 more source

The major histocompatibility complex of reindeer

open access: yesRangifer, 1990
The major histocompatibility complex (MHC) is a system of closely linked genes showing an extremely high degree of polymorphism. These genes are major elements in the government of specific immune reactions.
I. Olsaker, K. H. Røed
doaj   +1 more source

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]

open access: yes, 1992
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Reddehase, Matthias J.   +7 more
core   +1 more source

Congruence as a measurement of extended haplotype structure across the genome

open access: yesJournal of Translational Medicine, 2012
Background Historically, extended haplotypes have been defined using only a few data points, such as alleles for several HLA genes in the MHC. High-density SNP data, and the increasing affordability of whole genome SNP typing, creates the opportunity to ...
Baschal Erin E   +5 more
doaj   +1 more source

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