Results 51 to 60 of about 9,502,784 (300)
Major histocompatibility complex B variability in Korean native chicken breeds
Poultry Science, 2020 Adaptive genetic variations have direct influences on the fitness traits of the animal. The major histocompatibility complex B (MHC-B) region is responsible for adaptive and innate immune responses in chickens.
Prabuddha Manjula +3 more
doaj +1 more source
Non-major-histocompatibility-complex genetics of ankylosing spondylitis
, 2006 There is strong evidence from twin and family studies indicating that a substantial proportion of the heritability of susceptibility to ankylosing spondylitis (AS) and its clinical manifestations is encoded by non-major-histocompatibility-complex genes ...
Brown, Matthew A.
core +1 more source
A DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B and T cell responses in outbred animals [PDF]
, 2007 We developed a vaccine construct in which a BVP22 domain and an invariant-chain major histocompatibility complex class II-targeting motif capable of enhancing dendritic cell antigen uptake and presentation were fused to a sequence encoding a B- and T ...
Palmer, Guy H +19 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
HLA-check: evaluating HLA data from SNP information
BMC Bioinformatics, 2017 Background The major histocompatibility complex (MHC) region of the human genome, and specifically the human leukocyte antigen (HLA) genes, play a major role in numerous human diseases.
Marc Jeanmougin +3 more
doaj +1 more source
Comparative Genomics of the Major Histocompatibility Complex (MHC) of Felids
Frontiers in Genetics, 2022 This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered ...
Martin Plasil +7 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex
Brazilian Journal of Infectious DiseasesMany studies have tried to identify genetic markers for infectious diseases, some of them have focused on human leukocyte antigens (HLA). The products of HLA genes interact with surface-specific receptors of T lymphocytes, resulting in activation of the ...
Crésio Alves +4 more
doaj +1 more source
Molecular Genetics of Rheumatoid Arthritis and Future Prospectus in Pakistan
NUST Journal of Natural Sciences, 2010 The spectrum of rheumatic disease is wide and includes conditions with diverse pathology, although most have in common a heritable risk with a complex genetic basis.
Peter John +9 more
doaj +1 more source
, 2007 Phylogenetic trees based upon major histocompatibility complex (MHC) gene sequences, particularly those encompassing sites encoding the antigen recognition site, are often discordant with the species tree.
Kundu, S., Faulkes, C.
core +1 more source