Results 201 to 210 of about 235,574 (356)

Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex. [PDF]

open access: bronze, 1980
Caitríona Murray   +6 more
openalex   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Immunomodulatory Nanozymes Eradicate Intracellular Infections and Rescue Immunoparalysis for Treating Multidrug‐Resistant Bacterial Sepsis

open access: yesExploration, EarlyView.
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du   +19 more
wiley   +1 more source

"HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex". [PDF]

open access: yesFront Genet, 2023
Velastegui E   +4 more
europepmc   +1 more source

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

open access: yesGlia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy