Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex. [PDF]
Caitríona Murray+6 more
openalex +1 more source
Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li+6 more
wiley +1 more source
The Role of the Major Histocompatibility Complex Region on Chromosome 6 in Skin Atrophy: A Mendelian Randomization Study. [PDF]
Zhao C, Fan Z, Zhang R, Sun Y, Li WY.
europepmc +1 more source
Biochemical comparison of major histocompatibility complex molecules from different subspecies of Mus musculus: evidence for trans-specific evolution of alleles. [PDF]
B Arden, J Klein
openalex +1 more source
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du+19 more
wiley +1 more source
pMHChat, characterizing the interactions between major histocompatibility complex class II molecules and peptides with large language models and deep hypergraph learning. [PDF]
Ma J+5 more
europepmc +1 more source
"HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex". [PDF]
Velastegui E+4 more
europepmc +1 more source
Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz+9 more
wiley +1 more source