Results 21 to 30 of about 129,386 (217)
Трансплантология (Москва), 2023 Aim. To reveal the significance of the major histocompatibility complex and the human leukocyte antigen evolutionary divergence in transplantation of allogeneic hematopoietic stem cells.
F. A. Omarova +2 more
doaj +1 more source
Clinics, 2012 OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria)
Samuel Katsuyuki Shinjo +3 more
doaj +1 more source
The Marine Mammal Class II Major Histocompatibility Complex Organization
Frontiers in Immunology, 2019 Sirenians share with cetaceans and pinnipeds several convergent traits selected for the aquatic lifestyle. Living in water poses new challenges not only for locomotion and feeding but also for combating new pathogens, which may render the immune system ...
André Luiz Alves de Sá +7 more
doaj +1 more source
Major histocompatibility complex and its importance towards controlling infection
Asian Journal of Medical Sciences, 2017 It is well documented that infectious pathogen burden and infected cell mass determine the clinical severity of infectious diseases, however, the ability of the host to recognize and process antigens to produce antibodies or the cellular immune response ...
Langamba Angom Longjam
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Major histocompatibility complex B variability in Korean native chicken breeds
Poultry Science, 2020 Adaptive genetic variations have direct influences on the fitness traits of the animal. The major histocompatibility complex B (MHC-B) region is responsible for adaptive and innate immune responses in chickens.
Prabuddha Manjula +3 more
doaj +1 more source
Comparative Genomics of the Major Histocompatibility Complex (MHC) of Felids
Frontiers in Genetics, 2022 This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered ...
Martin Plasil +7 more
doaj +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
The major histocompatibility complex participates in Parkinson’s disease
Pharmacological ResearchParkinson’s disease (PD) is a common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra and the aggregation of alpha-synuclein (α-syn).
Rou Gu +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source