Results 81 to 90 of about 4,457 (177)

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 599-623, July/August 2026.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Endophyte‐induced systemic spatial reprogramming of metabolism in Populus trichocarpa roots under drought

open access: yesNew Phytologist, Volume 251, Issue 1, Page 438-454, July 2026.
Summary Beneficial, facultative endophytes help plants thrive in challenging environments by altering their host's metabolism, but how these cellular scale metabolic changes propagate to the systems biology scale is unknown. In this work, we employed a high‐resolution chemical imaging approach to map metabolic changes at the Populus trichocarpa root ...
Jayde Aufrecht   +9 more
wiley   +1 more source

Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications

open access: yesAnalytical Science Advances
Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues.
Toufik Mahamdi, Oscar Yanes
doaj   +1 more source

Assessment of hiPSC-derived kidney organoids from cryopreserved progenitors using MALDI-MSI

open access: yesHeliyon
Induced pluripotent stem cell (iPSC) derived kidney organoids are three-dimensional aggregates that self-organize in a permissive environment, and exhibit structural similarities to the adult kidney.
Loes E. Wiersma   +3 more
doaj   +1 more source

Matrix-assisted laser desorption/ionization mass spectrometry imaging for quorum sensing

open access: yesAMB Express
Quorum sensing (QS) is a complex communication system in bacteria, directing their response to the environment. QS is also one of the main regulators of bacterial biofilms’ formation, maturation and dispersion. Matrix-assisted laser desorption ionization
Christel Kuik   +4 more
doaj   +1 more source

Advances in Single-Cell Mass Spectrometry Imaging for Small Molecule Analysis

open access: yesZhipu Xuebao
Mass spectrometry imaging (MSI) has emerged as a powerful technique for label-free molecular mapping in biological tissues, enabling spatial analysis of small molecules at the single-cell level.
Xiang MEI   +3 more
doaj   +1 more source

MALDI-MSI Lipidomics of Lung Tissue v2

open access: yes
This protocol describes the procedure to obtain MALDI mass spectrometry images of lipids using a high mass resolution FTICR. This protocol is optimized for 12 µm sections of agarose-inflated and carboxymethyl cellulose-embedded fresh-frozen lung tissues. The embedding method is described in Lukowski et al.
Christopher R Anderton, Brittney Gorman
openaire   +1 more source

MALDI-MSI Lipidomics of Lung Tissue v1

open access: yes
This protocol describes the procedure to obtain MALDI mass spectrometry images of lipids using a high mass resolution FTICR. This protocol is optimized for 12 µm sections of agarose-inflated and carboxymethyl cellulose-embedded fresh-frozen lung tissues. The embedding method is described in Lukowski et al.
Christopher R Anderton, Brittney Gorman
openaire   +1 more source

Application of MALDI-MSI for detection of antimicrobial peptides in tissues of the marine invertebrate Arenicola marina [PDF]

open access: yesInvertebrate Survival Journal, 2016
Application of MALDI-MSI for detection of antimicrobial peptides in tissues of the marine invertebrate Arenicola marina AL Maltseva1 , VV Starunov1 , PA Zykin2 1 Department of Invertebrate Zoology, St Petersburg State University, St Petersburg ...
AL Maltseva, VV Starunov, PA Zykin
doaj  

MALDI Mass Spectrometry Imaging for the Simultaneous Location of Resveratrol, Pterostilbene and Viniferins on Grapevine Leaves

open access: yesMolecules, 2014
To investigate the in-situ response to a stress, grapevine leaves have been subjected to mass spectrometry imaging (MSI) experiments. The Matrix Assisted Laser Desorption/Ionisation (MALDI) approach using different matrices has been evaluated.
Loïc Becker   +4 more
doaj   +1 more source

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