Results 81 to 90 of about 187,471 (221)

Improved spectra for MALDI MSI of peptides using ammonium phosphate monobasic in MALDI matrix

, 2018
MALDI mass spectrometry imaging (MSI) enables analysis of peptides along with histology. However, there are several critical steps in MALDI MSI of peptides, one of which is spectral quality.
Aysel Ozpinar, Yasemin Ucal, Ozpinar, Aysel, Ucal, Yasemin   +3 more
core   +1 more source

MSI datasets - Data for lipid, protein and peptide MALDI MSI on rat brain cerebellum.

, 2023
Mis data for lipid, protein and peptide MALDI MSI on rat brain cerebellum sagittal ...
Lagache, Laurine
core   +1 more source

Comparative lipid profiling of murine and human atherosclerotic plaques using high-resolution MALDI MSI

Pflügers Archiv: European Journal of Physiology, 2021
The distribution of atherosclerotic lesions in the aorta and its branches of ApoE knockout (ApoE −/− ) mice is like that of patients with atherosclerosis.
Pegah Khamehgir-Silz, Stefanie Gerbig, Nadine Volk, Sabine Schulz, B. Spengler, M. Hecker, A. Wagner   +6 more
semanticscholar   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Lipidomic Typing of Colorectal Cancer Tissue Containing Tumour-Infiltrating Lymphocytes by MALDI Mass Spectrometry Imaging

Metabolites, 2021
Predicting the prognosis of colorectal cancer (CRC) patients remains challenging and a characterisation of the tumour immune environment represents one of the most crucial avenues when attempting to do so.
Vanna Denti, Allia Mahajneh, Giulia Capitoli, Francesca Clerici, Isabella Piga, Lisa Pagani, Clizia Chinello, Maddalena Maria Bolognesi, Giuseppe Paglia, Stefania Galimberti, Fulvio Magni, Andrew Smith   +11 more
doaj   +1 more source

Elucidating the spatial distribution of organic contaminants and their biotransformation products in amphipod tissue by MALDI- and DESI-MS-imaging

Ecotoxicology and Environmental Safety, 2023
The application of mass spectrometry imaging (MSI) is a promising tool to analyze the spatial distribution of organic contaminants in organisms and thereby improve the understanding of toxicokinetic and toxicodynamic processes.
Johannes Raths, Fernanda E. Pinto, Christian Janfelt, Juliane Hollender   +3 more
doaj   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Multiplexed discovery of sequence polymorphisms using base-specific cleavage and MALDI-TOF MS [PDF]

, 2005
Ehrich M, Böcker S, Boom D van den. Multiplexed discovery of sequence polymorphisms using base-specific cleavage and MALDI-TOF MS. Nucleic Acids Research.
Boom van den, D., Ehrich, Mathias, Böcker, S., Boom, Dirk van den, Ehrich, M., Böcker, Sebastian   +5 more
core   +1 more source

Visualizing the distribution of flavonoids in litchi (Litchi chinenis) seeds through matrix-assisted laser desorption/ionization mass spectrometry imaging

Frontiers in Plant Science, 2023
Flavonoids are one of the most important bioactive components in litchi (Litchi chinensis Sonn.) seeds and have broad-spectrum antiviral and antitumor activities.
Yukun Liu, Xiaofei Nie, Jilong Wang, Zhenqi Zhao, Zhimei Wang, Fang Ju   +5 more
doaj   +1 more source

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source