Results 71 to 80 of about 95,119 (201)
Journal of Pharmaceutical Analysis, 2023 Diabetic cardiomyopathy (DCM) is a metabolic disease and a leading cause of heart failure among people with diabetes. Mass spectrometry imaging (MSI) is a versatile technique capable of combining the molecular specificity of mass spectrometry (MS) with ...
Yanhua Liu +8 more
doaj +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer
, 2017 Fine needle aspiration (FNA) biopsies are the current gold-standard for the preoperative evaluation of thyroid nodules. However, a significant number of them (15-30%) are unable to be affirmatively diagnosed and are given an "indeterminate for malignancy" final report, meaning that the malignant nature of the thyroid nodule remains unknown and the ...
Mosele, N +4 more
openaire +2 more sources
, 2023 Neurotransmitters (NTs) and neuromodulators (NMs) are two of the most important neurochemicals in the brain, and their imbalances in specific brain regions are thought to underlie certain neurological disorders.
Xinxin Liu (534717) +6 more
core +1 more source
Perspectives of High‐Resolution Mass Spectrometry in Soil Science
Journal of Plant Nutrition and Soil Science, EarlyView.ABSTRACT Soil biogeochemical research requires specific, sensitive, and accurate methods to identify and quantify organic molecules in order to trace biochemical processes and assess element cycling in complex, heterogenous systems. High‐resolution mass spectrometry (HRMS) has evolved into a transformative tool for unraveling the complex chemical ...
Bruno Glaser +11 more
wiley +1 more source
Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI [PDF]
Methods, 2011 Characterising the protein signatures in tumours following vascular-targeted therapy will help determine both treatment response and resistance mechanisms. Here, mass spectrometry imaging and MS/MS with and without ion mobility separation have been used for this purpose in a mouse fibrosarcoma model following treatment with the tubulin-binding tumour ...
Cole, Laura +7 more
openaire +4 more sources
Analytical Science AdvancesMatrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI‐MSI) is an emerging imaging tool that allows visualisation of hundreds of analytes unbiasedly in a single experiment.
Yuen Tung Ngai +3 more
doaj +1 more source
, 2019 Low-molecular-weight (low-MW) compounds have many essential functions in biological processes, and the molecular imaging of as many low-MW compounds as possible is critical for understanding complex biological processes.
Xiaodong Wang (66801) +12 more
core +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Mass Spectrometry Reviews, EarlyView.Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source