Results 51 to 60 of about 187,471 (221)
Detection of honeybee venom in envenomed tissues by direct MALDI MSI [PDF]
Journal of the American Society for Mass Spectrometry, 2009 A new analytical approach using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) for the study of honeybee venom is shown. In vitro and in vivo models simulating the bee sting have been developed using live honeybees and, as the envenomation sites, pig ears and rat legs; MALDI MSI has been used to map, over time, the ...
Francese S. +5 more
openaire +3 more sources
Recent developments of MALDI MSI application in plant tissues analysis
Acta Biochimica Polonica, 2020 Mass spectrometry imaging (MSI) combined with matrix-assisted laser desorption/ionization (MALDI) is an efficient technology applied in plant metabolomics research. This technique allows for visualization of spatial distribution of metabolites such as: lipids, proteins, peptides and DNA sequences, by determining the x, y coordinates of the compounds ...
Katarzyna Susniak +4 more
openaire +3 more sources
Multifunctional Reactive MALDI Matrix Enabling High-Lateral Resolution Dual Polarity MSI and Lipid C=C Position-Resolved MS2I [PDF]
, 2020 Local lipid variations in tissues are readily revealed with mass spectrometry imaging (MSI) methods and resulting lipid distributions serve as bioanalytical signatures to reveal cell- or tissue-specific lipids.
Andreas H., Wagner +3 more
core +2 more sources
Scientific Reports, 2017 MALDI mass spectrometry imaging is able to simultaneously determine the spatial distribution of hundreds of molecules directly from tissue sections, without labeling and without prior knowledge.
M. Dilillo +9 more
doaj +1 more source
Proteomics, 2022 MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements.
T. S. Høiem +15 more
semanticscholar +1 more source
Mass Spectrometry Imaging of Flavonols and Ellagic Acid Glycosides in Ripe Strawberry Fruit
Molecules, 2020 Flavonols and ellagic acid glycosides are major phenolic compounds in strawberry fruit. They have antioxidant activity, show protective functions against abiotic and biotic stress, and provide health benefits.
Hirofumi Enomoto
doaj +1 more source
Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging
Pharmaceuticals, 2022 (1) Imaging of pharmaceutical compounds in tissue is an increasingly important subsection of Mass Spectrometry Imaging (MSI). Identifying proper target engagement requires MS platforms with high sensitivity and spatial resolution.
Andrew P. Bowman +5 more
doaj +1 more source
Journal of Fungi, 2020 A procedure for processing frozen rat lung tissue sections for scanning electron microscopy (SEM) from deeply frozen samples initially collected and stored for matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) was ...
Tereza Juříková +9 more
doaj +1 more source
Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues
Frontiers in Chemistry, 2022 Compared with conventional optical microscopy techniques, mass spectrometry imaging (MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique, which can sensitively and simultaneously detect, quantify, and map hundreds of ...
Xiaoping Zhu +6 more
doaj +1 more source
On-Tissue Derivatization of Lipopolysaccharide for Detection of Lipid A Using MALDI-MSI
Analytical Chemistry, 2020 We developed a method to directly detect and map the Gram-negative bacterial virulence factor lipid A derived from lipopolysaccharide (LPS) by coupling acid hydrolysis with matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI). As the structure of lipid A (endotoxin) determines the innate immune outcome during infection, the
Hyojik Yang +6 more
openaire +5 more sources