Results 31 to 40 of about 95,119 (201)

A Proof of Concept to Bridge the Gap between Mass Spectrometry Imaging, Protein Identification and Relative Quantitation: MSI~LC-MS/MS-LF

Proteomes, 2016
Mass spectrometry imaging (MSI) is a powerful tool to visualize the spatial distribution of molecules on a tissue section. The main limitation of MALDI-MSI of proteins is the lack of direct identification.
Laëtitia Théron, Delphine Centeno, Cécile Coudy-Gandilhon, Estelle Pujos-Guillot, Thierry Astruc, Didier Rémond, Jean-Claude Barthelemy, Frédéric Roche, Léonard Feasson, Michel Hébraud, Daniel Béchet, Christophe Chambon   +11 more
doaj   +1 more source

Mass Spectrometry Imaging as a Tool to Investigate Region Specific Lipid Alterations in Symptomatic Human Carotid Atherosclerotic Plaques

Metabolites, 2021
Atherosclerosis is characterized by fatty plaques in large and medium sized arteries. Their rupture can causes thrombi, occlusions of downstream vessels and adverse clinical events.
Francesco Greco, Laura Quercioli, Angela Pucci, Silvia Rocchiccioli, Mauro Ferrari, Fabio A. Recchia, Liam A. McDonnell   +6 more
doaj   +1 more source

Matrix-assisted laser desorption/ionisation mass spectrometry imaging and its development for plant protein imaging

Plant Methods, 2011
Matrix-Assisted Laser Desorption/Ionisation (MALDI) mass spectrometry imaging (MSI) uses the power of high mass resolution time of flight (ToF) mass spectrometry coupled to the raster of lasers shots across the cut surface of tissues to provide new ...
Millar A Harvey, Taylor Nicolas L, Grassl Julia   +2 more
doaj   +1 more source

MSI datasets - Data for lipid, protein and peptide MALDI MSI on rat brain cerebellum.

, 2023
Mis data for lipid, protein and peptide MALDI MSI on rat brain cerebellum sagittal ...
Lagache, Laurine
core   +1 more source

Regional N-glycan and lipid analysis from tissues using MALDI-mass spectrometry imaging

STAR Protocols, 2021
Summary: N-glycans and lipids are structural metabolites that play important roles in cellular processes. Both show unique regional distribution in tissues; therefore, spatial analyses of these metabolites are crucial to our understanding of cellular ...
Alexandra E. Stanback, Lindsey R. Conroy, Lyndsay E.A. Young, Tara R. Hawkinson, Kia H. Markussen, Harrison A. Clarke, Derek B. Allison, Ramon C. Sun   +7 more
doaj   +1 more source

Multifunctional Reactive MALDI Matrix Enabling High-Lateral Resolution Dual Polarity MSI and Lipid C=C Position-Resolved MS2I [PDF]

, 2020
Local lipid variations in tissues are readily revealed with mass spectrometry imaging (MSI) methods and resulting lipid distributions serve as bioanalytical signatures to reveal cell- or tissue-specific lipids.
Andreas H., Wagner, Sven, Heiles, Fabian, Wäldchen, Franziska, Mohr   +3 more
core   +2 more sources

Detection of honeybee venom in envenomed tissues by direct MALDI MSI [PDF]

Journal of the American Society for Mass Spectrometry, 2009
A new analytical approach using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) for the study of honeybee venom is shown. In vitro and in vivo models simulating the bee sting have been developed using live honeybees and, as the envenomation sites, pig ears and rat legs; MALDI MSI has been used to map, over time, the ...
Francese S., D. Lambardi, G. Mastrobuoni, LA MARCA, GIANCARLO, MONETI, GLORIANO, TURILLAZZI, STEFANO   +5 more
openaire   +3 more sources

Ultra-High Mass Resolution MALDI Imaging Mass Spectrometry of Proteins and Metabolites in a Mouse Model of Glioblastoma

Scientific Reports, 2017
MALDI mass spectrometry imaging is able to simultaneously determine the spatial distribution of hundreds of molecules directly from tissue sections, without labeling and without prior knowledge.
M. Dilillo, R. Ait-Belkacem, C. Esteve, D. Pellegrini, S. Nicolardi, M. Costa, E. Vannini, E. L. de Graaf, M. Caleo, L. A. McDonnell   +9 more
doaj   +1 more source

Mass Spectrometry Imaging of Flavonols and Ellagic Acid Glycosides in Ripe Strawberry Fruit

Molecules, 2020
Flavonols and ellagic acid glycosides are major phenolic compounds in strawberry fruit. They have antioxidant activity, show protective functions against abiotic and biotic stress, and provide health benefits.
Hirofumi Enomoto
doaj   +1 more source

Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections.

, 2022
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) allows spatial analysis of proteins, metabolites, or small molecules from tissue sections.
Belka, C., Baumeister, Philipp, Heider, Theresa, Unger, K., Riedl, T., Riedl, Tobias, Kreutzer, Lisa, Baumeister, P., Walch, Axel, Zitzelsberger, Horst, Klauschen, F., Heikenwälder, Mathias, Unger, Kristian, Hess, Julia, Klauschen, Frederick, Heider, T., Walch, A.K., Zitzelsberger, H., Weber, Peter, Kreutzer, L., Hess-Rieger, J., Weber, P., Belka, Claus, Heikenwaelder, M.   +23 more
core   +1 more source