Results 31 to 40 of about 4,457 (177)
Regional N-glycan and lipid analysis from tissues using MALDI-mass spectrometry imaging
STAR Protocols, 2021 Summary: N-glycans and lipids are structural metabolites that play important roles in cellular processes. Both show unique regional distribution in tissues; therefore, spatial analyses of these metabolites are crucial to our understanding of cellular ...
Alexandra E. Stanback +7 more
doaj +1 more source
Recent developments of MALDI MSI application in plant tissues analysis
Acta Biochimica Polonica, 2020 Mass spectrometry imaging (MSI) combined with matrix-assisted laser desorption/ionization (MALDI) is an efficient technology applied in plant metabolomics research. This technique allows for visualization of spatial distribution of metabolites such as: lipids, proteins, peptides and DNA sequences, by determining the x, y coordinates of the compounds ...
Katarzyna Susniak +4 more
openaire +3 more sources
Scientific Reports, 2017 MALDI mass spectrometry imaging is able to simultaneously determine the spatial distribution of hundreds of molecules directly from tissue sections, without labeling and without prior knowledge.
M. Dilillo +9 more
doaj +1 more source
Mass Spectrometry Imaging of Flavonols and Ellagic Acid Glycosides in Ripe Strawberry Fruit
Molecules, 2020 Flavonols and ellagic acid glycosides are major phenolic compounds in strawberry fruit. They have antioxidant activity, show protective functions against abiotic and biotic stress, and provide health benefits.
Hirofumi Enomoto
doaj +1 more source
Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging
Pharmaceuticals, 2022 (1) Imaging of pharmaceutical compounds in tissue is an increasingly important subsection of Mass Spectrometry Imaging (MSI). Identifying proper target engagement requires MS platforms with high sensitivity and spatial resolution.
Andrew P. Bowman +5 more
doaj +1 more source
Journal of Fungi, 2020 A procedure for processing frozen rat lung tissue sections for scanning electron microscopy (SEM) from deeply frozen samples initially collected and stored for matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) was ...
Tereza Juříková +9 more
doaj +1 more source
Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues
Frontiers in Chemistry, 2022 Compared with conventional optical microscopy techniques, mass spectrometry imaging (MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique, which can sensitively and simultaneously detect, quantify, and map hundreds of ...
Xiaoping Zhu +6 more
doaj +1 more source
Angewandte Chemie, EarlyView.We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan +5 more
wiley +2 more sources
Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations [PDF]
Chemistry and Physics of Lipids, 2012 Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has emerged as a novel powerful MS methodology that has the ability to generate both molecular and spatial information within a tissue section. Application of this technology as a new type of biochemical lipid microscopy may lead to new discoveries of the lipid metabolism
Louis J, Sparvero +7 more
openaire +2 more sources
BMC Zoology, 2020 Background Sexual behavior in Drosophila melanogaster flies is greatly influenced by chemical cues. In this study, a spatial distribution of female and male sex pheromones was investigated on the surface of virgin and mated six-day-old fruit flies ...
Filip Kaftan +5 more
doaj +1 more source