Results 21 to 30 of about 95,119 (201)

Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP

Nature Communications, 2021
MALDI-mass spectrometry imaging (MSI) can reveal the distribution of proteins in tissues but tools for protein identification and annotation are sparse.
G. Guo, M. Papanicolaou, N. J. Demarais, Z. Wang, K. L. Schey, P. Timpson, T. R. Cox, A. C. Grey   +7 more
doaj   +1 more source

Spatial Distribution and Migration Characteristic of Forchlorfenuron in Oriental Melon Fruit by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Foods, 2023
Forchlorfenuron is a widely used plant growth regulator to support the pollination and fruit set of oriental melons. It is critical to investigate the spatial distribution and migration characteristics of forchlorfenuron among fruit tissues to understand
Qi Wang, Xiaohui Li, Hongping Wang, Simeng Li, Chen Zhang, Xueying Chen, Jing Dong, Hua Shao, Jing Wang, Fen Jin   +9 more
doaj   +1 more source

Molecular Profiling of Glioblastoma Patient-Derived Single Cells Using Combined MALDI-MSI and MALDI-IHC. [PDF]

Anal Chem
In recent years, mass spectrometry-based imaging techniques have improved at unprecedented speeds, particularly in spatial resolution, and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) experiments can now routinely ...
Krestensen KK, Hendriks TFE, Grgic A, Derweduwe M, De Smet F, Heeren RMA, Cuypers E.   +6 more
europepmc   +2 more sources

Novel Blotting Method for Mass Spectrometry Imaging of Metabolites in Strawberry Fruit by Desorption/Ionization Using Through Hole Alumina Membrane

Foods, 2020
Mass spectrometry imaging (MSI) using matrix-assisted laser desorption/ionization (MALDI) is a powerful technique for visualizing metabolites in the strawberry fruit. During sample preparation for MALDI-MSI, sectioning of the samples is usually required.
Hirofumi Enomoto, Masahiro Kotani, Takayuki Ohmura   +2 more
doaj   +1 more source

Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma. [PDF]

PLoS ONE, 2017
Matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (MALDI-MSI) allows us to investigate the distribution of lipid molecules within tissues.
Leonardo Ermini, Elena Morganti, Alexander Post, Behzad Yeganeh, Isabella Caniggia, Michael Leadley, Claudia C Faria, James T Rutka, Martin Post   +8 more
doaj   +1 more source

Matrix-Free High-Resolution Atmospheric-Pressure SALDI Mass Spectrometry Imaging of Biological Samples Using Nanostructured DIUTHAME Membranes

Metabolites, 2021
Applications of mass spectrometry imaging (MSI), especially matrix-assisted laser desorption/ionization (MALDI) in the life sciences are becoming increasingly focused on single cell analysis.
Max A. Müller, Dhaka R. Bhandari, Bernhard Spengler   +2 more
doaj   +1 more source

Integrating UHPLC-MS and MALDI-MSI for Spatial Nucleoside Profiling in FFPE Breast Cancer: A Multimodal Molecular Pathology Framework. [PDF]

Anal Chem
Formalin-fixed, paraffin-embedded (FFPE) tissues constitute the primary material for diagnostic pathology and retrospective clinical research, yet their use in metabolomics remains limited due to molecular cross-linking and analyte degradation.
Wu J, Geisberger S, Mastrobuoni G, Lisek K, Raimundo S, Nebrich G, Grzeski M, Rajewsky N, Klauschen F, Klein O, Kempa S.   +10 more
europepmc   +2 more sources

MALDI Mass Spectrometry Imaging: A Potential Game-Changer in a Modern Microbiology

Cells, 2022
Nowadays, matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) is routinely implemented as the reference method for the swift and straightforward identification of microorganisms.
Maureen Feucherolles, Gilles Frache
doaj   +1 more source

MALDI-MSI - Cholesterol in Mouse Brain

, 2020
MALDI-MSI study on cholesterol in brain by Angelini et al.
Roberto Angelini
core   +3 more sources

Optimized protocol for MALDI MSI of N-glycans using an on-tissue digestion in fresh frozen tissue sections

Scientific Reports, 2023
Glycans play an important role in biology with multiple cellular functions ranging from cell signaling, mobility and growth to protein folding and localization.
Andrej Grgic, Kasper K. Krestensen, Ron M. A. Heeren   +2 more
doaj   +1 more source