Results 41 to 50 of about 2,744,238 (299)

Alterations in the protein lactylation landscape of sperm from patients with varicocele-associated asthenozoospermia

Frontiers in Endocrinology
BackgroundsVaricocele is a leading cause of male infertility, primarily manifesting as asthenozoospermia. The underlying molecular mechanisms remain unclear, and the potential role of protein lactylation in this condition is unknown.MethodsWe performed a
Heran Cao, Xiaohua Liu, Hua Nie, Shenghui Zhu, Shujuan Liu, Yu Zhou, Chunjie Ma, Huang Liu, Weibing Qin   +8 more
doaj   +1 more source

Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm

Frontiers in Endocrinology, 2020
Aim: Evidence suggests that bisphenol A diglycidyl ether (BADGE), bisphenol A (BPA), and BPA analogs can interfere with human male fertility. However, the effect directly on human sperm function is not known.
Anders Rehfeld, Anders Rehfeld, A. M. Andersson, A. M. Andersson, N. E. Skakkebæk, N. E. Skakkebæk   +5 more
doaj   +1 more source

AMH concentrations in infancy and mid-childhood predict ovarian activity in adolescence: A long-term longitudinal study of healthy girlsResearch in context

EClinicalMedicine, 2023
Summary: Background: Anti-Müllerian hormone (AMH) is produced by granulosa cells in small growing ovarian follicles. In adult women, serum concentrations of AMH reflect the ovarian reserve of resting primordial follicles, and low AMH is associated with ...
Casper P. Hagen, Margit Bistrup Fischer, Christine Wohlfahrt-Veje, Maria Assens, Alexander S. Busch, Anette Tønnes Pedersen, Anders Juul, Katharina M. Main   +7 more
doaj   +1 more source

Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome

Endocrine Connections, 2020
Puberty marks a transition period, which leads to the attainment of adult sexual maturity. Timing of puberty is a strongly heritable trait. However, large genetic association studies can only explain a fraction of the observed variability and striking ...
Kristian Almstrup, Hanne Frederiksen, Anna-Maria Andersson, Anders Juul   +3 more
doaj   +1 more source

Deciphering Sex-Specific Differentiation of Human Fetal Gonads: Insight From Experimental Models

Frontiers in Cell and Developmental Biology, 2022
Sex-specific gonadal differentiation is initiated by the expression of SRY in male foetuses. This promotes a signalling pathway directing testicular development, while in female foetuses the absence of SRY and expression of pro-ovarian factors promote ...
Malene Lundgaard Riis, Malene Lundgaard Riis, Anne Jørgensen, Anne Jørgensen   +3 more
doaj   +1 more source

Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

Endocrine Connections, 2018
Introduction: Bisphenol A and several of the most commonly used phthalates have been associated with adverse metabolic health effects such as obesity and diabetes.
Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen, Anders Juul   +4 more
doaj   +1 more source

Circulating levels and the bioactivity of miR-30b increase during pubertal progression in boys

Frontiers in Endocrinology, 2023
BackgroundPuberty marks the transition from childhood to adulthood and is initiated by activation of a pulsatile GnRH secretion from the hypothalamus.
Nina Mørup, Nina Mørup, Rytis Stakaitis, Rytis Stakaitis, Rytis Stakaitis, Ailsa Maria Main, Ailsa Maria Main, Ailsa Maria Main, Ieva Golubickaite, Ieva Golubickaite, Ieva Golubickaite, Casper P. Hagen, Casper P. Hagen, Anders Juul, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Kristian Almstrup   +18 more
doaj   +1 more source

“Seminal testosterone”, rising viewpoint of local spermatogenesis in nonobstructive azoospermia: One center long-term bidirectional cohort study

Frontiers in Endocrinology, 2022
ObjectiveReproductive hormones are a traditional good method to evaluate spermatogenesis but might not accurately represent local spermatogenesis. To find a more accurate method, seminal reproductive hormones were studied.MethodsA bidirectional cohort ...
Huang Liu, Houbin Zheng, Yuehua Li, Yuqian Tang, Hongbo Peng, Qianyi Li, Jiaming Zhuang, Yingyi Zhou, Yu Zhou, Xiang’an Tu, Xinzong Zhang   +10 more
doaj   +1 more source

Male-killing bacteria in insects: mechanisms, incidence and implications [PDF]

, 2000
Bacteria that are vertically transmitted through female hosts and kill male hosts that inherit them were first recorded in insects during the 1950s. Recent studies have shown these "male-killers" to be diverse and have led to a reappraisal of the biology
Hurst, GDD, Jiggins, FM, Gregory D.D. Hurst, Francis M. Jiggins   +3 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source