Results 51 to 60 of about 2,744,238 (299)

Effects of Qilin pills on spermatogenesis, reproductive hormones, oxidative stress, and the TSSK2 gene in a rat model of oligoasthenospermia

BMC Complementary Medicine and Therapies, 2020
s Background Qilin pills (QLPs), a classic Traditional Chinese Medicine (TCM) formula for treating male infertility, effectively improve semen quality in clinical trials.
Kaishu Zhang, Longlong Fu, Qi An, Weihong Hu, Jianxin Liu, Xiuming Tang, Yu Ding, Wenhong Lu, Xiaowei Liang, Xuejun Shang, Yiqun Gu   +10 more
doaj   +1 more source

Non-Classic Congenital Adrenal Hyperplasia in Two Adolescents With Gender Dysphoria

Journal of Psychosexual Health, 2021
The care of transgender individuals is multidisciplinary including medical, surgical, psychiatric, and psychological health professionals. We here report 2 cases of nonclassic congenital adrenal hyperplasia (CAH) coincidently discovered during the ...
Emma Wall, Lise Aksglaede, Mette Ewers Haahr, Peter Christiansen, Katharina M. Main   +4 more
doaj   +1 more source

Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study

Frontiers in Pharmacology, 2022
Objective: The aim of the study was to explore the evidence of JWRJD in the treatment of cryptozoospermia.Methods: A total of 162 cryptozoospermia patients with varicocele who refused to undergo surgery were included from January 2021 to December 2021 ...
Huang Liu, Huang Liu, Zhongwang Huang, Houbin Zheng, Zhiyong Zhu, Hui Yang, Xingzhang Liu, Tao Pang, Liping He, Hai Lin, Lei Hu, Qingqi Zeng, Qingqi Zeng, Lanying Han   +13 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Cell Death and Disease
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis.
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup   +7 more
doaj   +1 more source

Is age a critical indicator for determining the optimal abstinence duration in patients undergoing sperm acquisition?

Frontiers in Reproductive Health
IntroductionSperm cryopreservation is increasingly recognized as a key strategy for fertility preservation, particularly for male infertility patients who may benefit from assisted reproductive technology (ART). However, the optimal abstinence period for
Yifu Wang, Shenghui Zhu, Houbin Zheng, Hai Lin, Zhiyong Zhu, Huang Liu, Yu Zhou   +6 more
doaj   +1 more source

AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up

Frontiers in Endocrinology, 2023
Turner syndrome (TS) is a chromosomal disorder that affects about 1 in 2500 female births and is characterized by the partial or complete absence of the second X chromosome. Depending on karyotype, TS is associated with primary ovarian insufficiency (POI)
Casper P. Hagen, Casper P. Hagen, Margit Bistrup Fischer, Margit Bistrup Fischer, Gylli Mola, Gylli Mola, Theis Bech Mikkelsen, Theis Bech Mikkelsen, Line Hartvig Cleemann, Line Hartvig Cleemann, Claus Højbjerg Gravholt, Claus Højbjerg Gravholt, Mette H. Viuff, Anders Juul, Anders Juul, Anders Juul, Anette Tønnes Pedersen, Katharina Maria Main, Katharina Maria Main, Katharina Maria Main   +19 more
doaj   +1 more source

The somatic cost of reproduction: what determines reproductive effort in prime-aged fallow bucks? [PDF]

, 2003
The somatic costs of reproduction are important for understanding the relationship between sexual selection and life-history evolution, and there are two main hypotheses used to explain the pattern of reproductive effort in ungulates.
Hayden, T J, Hayden, TJ, Naulty, F, McElligott, AG, Clarke, WV, McElligott, A G, Clarke, W V   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source