Results 51 to 60 of about 1,065,944 (354)

Circulating levels and the bioactivity of miR-30b increase during pubertal progression in boys

Frontiers in Endocrinology, 2023
BackgroundPuberty marks the transition from childhood to adulthood and is initiated by activation of a pulsatile GnRH secretion from the hypothalamus.
Nina Mørup, Nina Mørup, Rytis Stakaitis, Rytis Stakaitis, Rytis Stakaitis, Ailsa Maria Main, Ailsa Maria Main, Ailsa Maria Main, Ieva Golubickaite, Ieva Golubickaite, Ieva Golubickaite, Casper P. Hagen, Casper P. Hagen, Anders Juul, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Kristian Almstrup   +18 more
doaj   +1 more source

“Seminal testosterone”, rising viewpoint of local spermatogenesis in nonobstructive azoospermia: One center long-term bidirectional cohort study

Frontiers in Endocrinology, 2022
ObjectiveReproductive hormones are a traditional good method to evaluate spermatogenesis but might not accurately represent local spermatogenesis. To find a more accurate method, seminal reproductive hormones were studied.MethodsA bidirectional cohort ...
Huang Liu, Houbin Zheng, Yuehua Li, Yuqian Tang, Hongbo Peng, Qianyi Li, Jiaming Zhuang, Yingyi Zhou, Yu Zhou, Xiang’an Tu, Xinzong Zhang   +10 more
doaj   +1 more source

Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study

Frontiers in Pharmacology, 2022
Objective: The aim of the study was to explore the evidence of JWRJD in the treatment of cryptozoospermia.Methods: A total of 162 cryptozoospermia patients with varicocele who refused to undergo surgery were included from January 2021 to December 2021 ...
Huang Liu, Huang Liu, Zhongwang Huang, Houbin Zheng, Zhiyong Zhu, Hui Yang, Xingzhang Liu, Tao Pang, Liping He, Hai Lin, Lei Hu, Qingqi Zeng, Qingqi Zeng, Lanying Han   +13 more
doaj   +1 more source

Thyroid and male reproduction

Indian Journal of Endocrinology and Metabolism, 2014
Male reproduction is governed by the classical hypothalamo-hypophyseal testicular axis: Hypothalamic gonadotropin releasing hormone (GnRH), pituitary luteinizing hormone (LH) and follicle stimulating hormone (FSH) and the gonadal steroid, principally, testosterone.
Anand Kumar, Skand Shekhar, Bodhana Dhole   +2 more
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Cell Death and Disease
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis.
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup   +7 more
doaj   +1 more source

Free testosterone and cardiometabolic parameters in men: comparison of algorithms

Endocrine Connections, 2021
Objective: Calculating the free testosterone level has gained increasing interest and different indirect algorithms have been suggested. The objective was to compare free androgen index (FAI), free testosterone estimated using the linear binding model ...
Stine A Holmboe, Ravi Jasuja, Brian Lawney, Lærke Priskorn, Niels Joergensen, Allan Linneberg, Tina Kold Jensen, Niels Erik Skakkebæk, Anders Juul, Anna-Maria Andersson   +9 more
doaj   +1 more source

Estrogens and male reproduction [PDF]

, 2009
The chapter deals with the study of estrogen role in male reproduction, in particulare the role on hypothalamic-pituitary-gonadal ...
CARANI, Cesare, MADEO, Bruno, ROCHIRA, Vincenzo, ZIRILLI, Lucia   +3 more
core  

Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect [PDF]

, 2018
Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system.
Dickinson, Matthew E., Franco, Aldina, Gage, Matthew J. G., Godwin, Joanne L., Hebberecht, Laura, Lumley, Alyson J., Michalczyk, Łukasz, Sales, Kris, Thomas, Paul, Vasudeva, Ramakrishnan   +9 more
core   +4 more sources