Results 61 to 70 of about 221,321 (308)
Free testosterone and cardiometabolic parameters in men: comparison of algorithms
Endocrine Connections, 2021 Objective: Calculating the free testosterone level has gained increasing interest and different indirect algorithms have been suggested. The objective was to compare free androgen index (FAI), free testosterone estimated using the linear binding model ...
Stine A Holmboe +9 more
doaj +1 more source
Reproductive Technologies for Male Infertility [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2001 The introduction of intracytoplasmic sperm injection (ICSI) in 1992 has revolutionized the treatment of male infertility (1) and has allowed couples whose only prior options were donor insemination to achieve pregnancies or adoption. Although in vitro fertilization (IVF) and related procedures have been used in the past for the treatment of male ...
O, Khorram +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Presence of parabens, phenols and phthalates in paired maternal serum, urine and amniotic fluid
Environment International, 2022 Objective: To examine whether selected endocrine disrupting chemicals were present in pregnant women and passed through the placental barrier to amniotic fluid, potentially exposing the developing fetus.
Elvira V. Bräuner +6 more
doaj +1 more source
Aging and the Male Reproductive System [PDF]
Endocrine Reviews, 2019 This narrative review presents an overview of current knowledge on fertility and reproductive hormone changes in aging men, the factors driving and modulating these changes, their clinical consequences, and the benefits and risks of testosterone (T) therapy. Aging is accompanied by moderate decline of gamete quality and fertility.
Jean-Marc Kaufman +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
BMC Pregnancy and ChildbirthBackground Polycystic ovarian syndrome (PCOS) is a common endocrine and metabolic disease in women. Hyperandrogenaemia (HA) and insulin resistance (IR) are the basic pathophysiological characteristics of PCOS.
Mengge Gao +6 more
doaj +1 more source
Endocrine Connections, 2018 Objective: Only a few genetic loci are known to be associated with male pubertal events. The ability of excreting testosterone (T) and other steroids in the urine depends on sulfation and glucuronidation.
Annette Mouritsen +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Leydig cells (Lc), located in the interstitial space of the testis between seminiferous tubules, produce 95% of testosterone in male individuals, which is pivotal for male sexual differentiation, spermatogenesis, and maintenance of the male secondary sex
Yinchuan Li +10 more
doaj +1 more source
Metabolism in Male Reproductive Aging
Advances in Geriatric Medicine and Research, 2021 Similar to female reproductive health, male reproductive health declines with increasing age, albeit in a more gradual way. In the US, the average age of first-time fathers has been steadily increasing since 1980. This is concerning because increasing paternal age is positively correlated with reduced sperm chromatin quality and higher numbers of DNA ...
Meyer, Ralph G., Meyer-Ficca, Mirella L.
openaire +2 more sources