Male mutation bias and possible long-term effects of human activities. [PDF]
, 2010 The ability of a population to adapt to changing environments depends critically on the amount and kind of genetic variability it possesses. Mutations are an important source of new genetic variability and may lead to new adaptations, especially if the ...
Cotton, S., Wedekind, C.
core +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Molecular evolution of candidate male reproductive genes in the brown algal model Ectocarpus [PDF]
, 2016 Background: Evolutionary studies of genes that mediate recognition between sperm and egg contribute to our understanding of reproductive isolation and speciation. Surface receptors involved in fertilization are targets of sexual selection, reinforcement,
De Clerck, Olivier +2 more
core +6 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Endocrine Connections, 2017 Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm ...
A Rehfeld +5 more
doaj +1 more source
Male reproductive pattern in a polygynous ungulate with a slow life-history: the role of age, social status and alternative mating tactics [PDF]
, 2018 According to life-history theory age-dependent investments into reproduction are thought to co-vary with survival and growth of animals. In polygynous species, in which size is an important determinant of reproductive success, male reproduction via ...
Biebach, Iris +7 more
core
Reproductive Market Values Explain Post-reproductive Lifespans in Men [PDF]
, 2016 Post-reproductive lifespans (PRLSs) of men vary across traditional societies. We argue that if sexual selection operates on male age-dependent resource availability (or 'reproductive market values') the result is variation in male late-life reproduction ...
Migliano, AB, Vinicius, L
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Nectar amino acids enhance reproduction in male butterflies [PDF]
, 2018 After over 30years of research, it was recently shown that nectar amino acids increase female butterfly fecundity. However, little attention has been paid to the effect of nectar amino acids on male butterfly reproduction.
Cahenzli, Fabian, Erhardt, Andreas
core
Male-killing endosymbionts: influence of environmental conditions on persistence of host metapopulation [PDF]
, 2008 Background: Male killing endosymbionts manipulate their arthropod host reproduction by only allowing female embryos to develop into infected females and killing all male offspring.
Bonte, Dries +2 more
core +3 more sources