Results 81 to 90 of about 2,744,238 (299)

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

open access: yesEndocrine Connections, 2017
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm ...
A Rehfeld   +5 more
doaj   +1 more source

Depigmented wing patch size is a condition-dependent indicator of viability in male collared flycatchers [PDF]

open access: yes, 2003
Honesty of sexual advertisement is thought to be the result of signalling costs. Because production costs of depigmented plumage patches are probably very low, their role as honest signals of individual quality has been questioned. Costs of bearing these
Hegyi, Gergely   +4 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Extended indications for sperm retrieval: summary of current literature [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Sperm retrieval combined with intracytoplasmic sperm injection (ICSI) is the treatment of choice for couples with untreatable azoospermia-related infertility. However, an increasing body of evidence has been mounting, suggesting that ICSI with testicular
Sandro C. Esteves, Matheus Roque
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Effect of Male Body Size on Female Reproduction in Pyrrhocoris apterus (L.) (Heteroptera, Pyrrhocoridae)

open access: yes, 2022
Females and males of the abundant heteropteran species Pyrrhocoris apterus (L.) mate with the larger of the available partners. The male benefits from copulation with a large female, which is more productive than a small female.
Martinkova, Zdenka   +3 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Dossier : actualités en reproduction équine

open access: yes, 1999
La production par une jument d’un poulain par an (et pourquoi pas de plusieurs) avec de la semence d’étalon conservée fraîche ou congelée est l’objectif appliqué actuel de toutes les équipes de recherche.
Equipe Reproduction Equine, -   +1 more
core   +1 more source

Health is male's business too : NT Indigenous Male Health Conference, Tennant Creek, 29-31 August, 2000 : a report on the indigenous male health movement in the Northern Territory.

open access: yes, 2000
This conference report has been prepared by the Male Health Policy Unit, within Territory Health Services, on behalf of the NT Indigenous Male Health Committee. It is essentially a descriptive recording of the information exchanged, the issues raised and

core  

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