Results 11 to 20 of about 20,100 (250)
Significance of Polyspikes on Electroencephalography in Children with Focal Epilepsy [PDF]
Annals of Child Neurology, 2022 Purpose Epilepsy is one of the most common neurological disorders in both adults and children. After detailed history-taking, electroencephalography (EEG) is the most important investigation in the evaluation of epilepsy patients.
Ara Ko +6 more
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Malformations of Cortical Development
Brain Pathology, 2012 AbstractStructural abnormalities of the brain are increasingly recognized in patients that suffer from pharmacoresistant focal epilepsies by applying high‐resolution imaging techniques. In many of these patients, epilepsy surgery results in control of seizures.
Aronica, Eleonora +2 more
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Focal Cortical Dysplasia in Pediatric Epilepsy [PDF]
Annals of Child Neurology, 2019 Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often explosive from their onset. This review summarizes
Sun Ah Choi, Ki Joong Kim
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Focal cortical dysplasia: Updates
Indian Journal of Pathology and Microbiology, 2022 Focal cortical dysplasias (FCDs) represent the third most frequent cause of drug-resistant focal epilepsy in adults (after hippocampal sclerosis and tumours) submitted to surgery, and the most common in the pediatric age group.
Jorge Pinheiro, Mrinalini Honavar
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Malformations of Cortical Development [PDF]
The Neurologist, 2008 Malformations of cortical development (MCD) are increasingly recognized as an important cause of epilepsy and developmental delay. MCD encompass a wide spectrum of disorders with various underlying genetic etiologies and clinical manifestations. High resolution imaging has dramatically improved our recognition of MCD.This review will provide a brief ...
Trudy, Pang, Ramin, Atefy, Volney, Sheen
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Fetal Brain Development: Regulating Processes and Related Malformations
Life, 2022 This paper describes the contemporary state of knowledge regarding processes that regulate normal development of the embryonic–fetal central nervous system (CNS).
Zvi Leibovitz +2 more
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Cortical Clefts and Cortical Bumps: A Continuous Spectrum [PDF]
Journal of Clinical and Diagnostic Research, 2016 Cortical ‘clefts’ (schizencephaly) and cortical ‘bumps’ (polymicrogyria) are malformations arising due to defects in postmigrational development of neurons.
Asthik Biswas +3 more
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Surgery for Cortical Malformations Causing Epilepsy
Pediatric Neurology Briefs, 2000 The results of surgical treatment for malformations of cortical development (MCD) causing refractory epilepsy are reviewed from the Institute of Neurology, Queen Square, London, UK.
J Gordon Millichap
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Modeling Somatic Mutations Associated With Neurodevelopmental Disorders in Human Brain Organoids
Frontiers in Molecular Neuroscience, 2022 Neurodevelopmental disorders (NDDs) are a collection of diseases with early life onset that often present with developmental delay, cognitive deficits, and behavioral conditions.
Bipan K. Deb +3 more
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Epilepsy with SLC35A2 Brain Somatic Mutations in Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) [PDF]
Annals of Child Neurology, 2022 Purpose This study presents the characteristics of patients with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) with SLC35A2 somatic variants in the brain who underwent epilepsy surgery and showed clinical
Hee-Jeong Kang +8 more
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