Results 91 to 100 of about 180,373 (302)

Maternal erythrocyte malondialdehyde level in preeclampsia prediction: a longitudinal study

, 2003
We aimed to determine the value of maternal erythrocyte malondialdehyde levels in the prediction of preeclampsia. 110 healthy women were included in this prospective study.Maternal erythrocyte malondialdehyde levels were measured at each trimester of ...
Demir, I, Ozcelik, Bülent, Tayyar, Mehmet, Saraymen, Recep, Serin, Ibrahim Serdar, Basbug, Mustafa, Narin, Figen   +6 more
core   +1 more source

Thyroid Disorders and the Level of Malondialdehyde [PDF]

, 2009
Background: Free radicals have been implicated in many pathological processes, including ischemia, inflammation, and malignancy. The free radicals may affect tissues damage by lipid peroxidation which generate malondialdehyde (MDA) as a by byproduct of ...
Hedef D. El-Yassin, Eham A. Ali, Yildiz H. Tahseen   +2 more
core   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Relationship Between Oxidative Stress and Severity of Diabetic Foot Ulcers Among Patients With Type‐2 Diabetes Mellitus in Japan: A Cross‐Sectional Study

Health Science Reports
Background Delayed healing of diabetic foot ulcers (DFUs) is associated with significant morbidity, and oxidative stress (OS) induced by a diabetic state is considered an essential factor in the development of DFUs.
Amos Tinashe Nyamadzawo, Junko Nishio, Toshiko Ogawa, Shinobu Okada   +3 more
doaj   +1 more source

Rapid Kinetic Fluorogenic Quantification of Malondialdehyde in Ground Beef

Foods
Malondialdehyde (MDA), a mutagenic and carcinogenic compound, is widely studied in the meat industry and lipid peroxidation research due to its implications for food quality and safety.
Keshav Raj Bhandari, Max Wamsley, Bindu Nanduri, Willard E. Collier, Dongmao Zhang   +4 more
doaj   +1 more source

Influence of Intestinal Strangulation Release on Ischemia-reperfusion Injury in Sprague Dawley Rats

The Annals of African Surgery, 2021
Background: In intestinal ischemia, reperfusion towards the injured intestine can cause further injury to the intestine itself and to remote organs. This research aimed to evaluate the influence of intestinal strangulation release (SR) before resection ...
Ahmad Yani, Dorothy Dorothy, Rizky Amaliah   +2 more
doaj  

Sialic acid accelerates the electrophoretic velocity of injured dorsal root ganglion neurons

Neural Regeneration Research, 2015
Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain.
Chen-xu Li, Guo-ying Ma, Min-fang Guo, Ying Liu   +3 more
doaj   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Advanced Science, EarlyView.
In this study, MPDA NPs were engineered to encapsulate CTT. To further increase renal accumulation of CTT, L‐serine was conjugated to the surface of the MPDA nanoparticles (CTT/MPDA@L‐Ser NPs). CTT/MPDA@L‐Ser NPs inhibit DPEP1 activity, thereby restoring ferroptosis defense mechanisms through upregulation of GPX4 and SLC7A11 expression, ultimately ...
Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu   +12 more
wiley   +1 more source