Results 71 to 80 of about 207,180 (311)

Paralytic shellfish toxins and ocean warming: bioaccumulation and ecotoxicological responses in jujvenile Gilthead Seabream (Sparus aurata) [PDF]

, 2019
Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety ...
Anacleto, Patrícia, Barbosa, Vera, Marques, António, Maulvault, Ana Luísa, Pousão-Ferreira, Pedro, Reis Costa, Pedro, Santos, Marta   +6 more
core   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Serum malondialdehyde concentration in babies with hyperbilirubinaemia [PDF]

Archives of Disease in Childhood - Fetal and Neonatal Edition, 1999
AIM To determine lipid peroxide concentrations in the first 10 days of life. METHODS Malondialdehyde concentrations were investigated in neonates with or without hyperbilirubinaemia during the first 10 days of life.
Yigit, S, Yurdakok, M, Kilinc, K, Oran, O, Erdem, G, Tekinalp, G   +5 more
openaire   +3 more sources

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

The Influence of Ethanolic Extract of Hypericum Perforatum (St. John's wort) on Growth Performance, Serum Metabolites, Fat Deposition, Immunity, and Lipid Peroxidation in Broiler Chickens

Veterinary Medicine and Science
Background Having bioactive components such as hypericin, hyperforin and quercetin has enabled Hypericum perforatum (HP) to show antioxidant, antiviral and hypocholesterolemic effects in different animal species.
Mohammad Ali Behroozilak, Seyed Adel Moftakharzadeh, Morteza Behroozlak, Vahid Vahedi, Somayeh Bakhshalizadeh   +4 more
doaj   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Estimation of serum malondialdehyde in potentially malignant disorders and post-antioxidant treated patients: A biochemical study

Contemporary Clinical Dentistry, 2012
Background: Tobacco causes the generation of free radicals and reactive oxygen species (ROS) which are responsible for the high rate of lipid peroxidation.
Deepa D′souza, G Subhas Babu, Shishir Ram Shetty, Preethi Balan   +3 more
doaj   +1 more source

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Infant Milk Formulas: Effect of Storage Conditions on the Stability of Powdered Products towards Autoxidation

Foods, 2015
Thirty samples of powdered infant milk formulas containing polyunsaturated fatty acids (PUFAs) have been stored at four different temperatures (20, 28, 40 and 55 °C) and periodically monitored for their malondialdehyde (MDA) content up to one year.
Stefania Cesa, Maria Antonietta Casadei, Felice Cerreto, Patrizia Paolicelli   +3 more
doaj   +1 more source