Results 11 to 20 of about 138,770 (255)

Malondialdehyde-Induced Post-translational Modifications in Hemoglobin of Smokers by NanoLC–NSI/MS/MS Analysis

open access: yes, 2022
Malondialdehyde (MDA) is the most abundant α,β-unsaturated aldehyde generated from endogenous peroxidation of polyunsaturated fatty acids and is present in cigarette smoke.
Hauh-Jyun Candy Chen (1456144)   +4 more
core   +1 more source

Protein carbonyl products, malondialdehyde, glutathione and vitamins C/E of breast cancer patients subjected to chemotherapy

open access: yes, 2022
Introduction: Various endogenous and exogenous processes contribute to the production of oxidative stress, of which anticancer drugs may be one. This study aimed at evaluating the effect of breast cancer chemotherapy on oxidative stress.
Itamar Luís Gonçalves   +7 more
core   +1 more source

Malondialdehyde‐Acetaldehyde Adducts and Anti–Malondialdehyde‐Acetaldehyde Antibodies in Rheumatoid Arthritis [PDF]

open access: yesArthritis & Rheumatology, 2015
ObjectiveMalondialdehyde‐acetaldehyde (MAA) adducts are a product of oxidative stress associated with tolerance loss in several disease states. This study was undertaken to investigate the presence of MAA adducts and circulating anti‐MAA antibodies in patients with rheumatoid arthritis (RA).MethodsSynovial tissue from patients with RA and patients with
Geoffrey M, Thiele   +15 more
openaire   +2 more sources

Antioxidant status in acute stroke patients and patients at stroke risk [PDF]

open access: yes, 2004
Background and Purpose: Antioxidant enzymes like copper/ zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular ...
Haberl, R. L.   +9 more
core   +1 more source

Response to “Malondialdehyde-Induced Post-Translational Modification of Human Hemoglobin”

open access: yes, 2023
Although malondialdehyde and methylglyoxal have the same molecular formula, they have different chemistry in forming protein adducts. The major lysine adduct of malondialdehyde in hemoglobin is the N-propenal type, while that of methylglyoxal is N6-(1 ...
Yan-Ling Liao   +3 more
core   +1 more source

Malondialdehyde: A Possible Marker of Ageing

open access: yesGerontology, 2002
<i>Background:</i> Numerous recent studies have suggested that oxidative damage may be important in the ageing process, and lipid peroxidation is an important biological consequence of oxidative cellular damage. <i>Objective:</i> The aim of this work was to analyze the activities of the two protective enzymes, superoxide ...
Gil, P.   +3 more
openaire   +3 more sources

Variations of malondialdehyde in pre-eclampsia [PDF]

open access: yesHypertension in Pregnancy, 2016
Malondialdehyde, as a biomarker of oxidative stress in pre-eclampsia, is discussed in terms of the determination methods, the validity of the obtained data, and variations in different studies, and it is concluded that there is a need for re-validation of the analytical methods and re-evaluation of its role as a biomarker of oxidative stress.
Maryam, Khoubnasabjafari   +2 more
openaire   +2 more sources

Effect of antibiotics on polymorphonuclear leukocyte functions and myeloperoxidase activity, glutathione and malondialdehyde levels in allergic asthma

open access: yes, 2015
We investigated the effect of ciprofloxacin, rifampicine and doxycycline on myeloperoxidase (MPO) activity, glutathione (GSH) and malondialdehyde (MDA) levels in allergic asthma patients and healthy volunteers.
SOYOĞUL GÜRER, ÜMRAN   +2 more
core   +1 more source

ANALYSIS OF MALONDIALDEHYDE LEVELS IN CHILDREN WITH BETA THALASSEMIA: A CROSS-SECTIONAL STUDY [PDF]

open access: yes, 2023
Beta thalassemia is an autosomal recessive genetic condition affecting people worldwide, including in Indonesia. Malondialdehyde levels, a peroxidation product, can be used to see if there is an iron buildup in the body due to lifelong transfusions. This
Alaydrus, Syarifah Raehana Mardiah   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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