Results 31 to 40 of about 180,373 (302)

Hydroxychloroquine Mitigates Cytokine Storm and Prevents Critical Illness Neuromyopathy in a Rat Sepsis Model

Medicina
Background and Objectives: It is known that critical illness and associated neuromuscular problems begin to appear in patients hospitalized in the intensive care unit (ICU) for more than a week.
Elif Eygi, Onur Kucuk, Semih Aydemir, Merve Atilgan, Recep Dokuyucu, Oytun Erbas   +5 more
doaj   +1 more source

Effect of Oxidative Stress and dyslipidemia in hypertensive Iraqi patients [PDF]

مجلة جامعة الانبار للعلوم الصرفة
Hypertension is a dangerous health issue, mostly due to its asymptomatic nature. The present study was designed to assess the malondialdehyde (MDA) as an indicator for oxidative stress and lipid profile in patients with hypertension in Anbar, Iraq.
Amna Mohammed, Maryam Salman, Mohammed Dawood   +2 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Thiamethoxam Application Improves Yield and Drought Resistance of Potatoes (Solanum tuberosum L.)

Plants
(1) Background: Potato is the most important tuber crop in the world that can contribute to food security. However, the crop has been shown to be sensitive to drought and its yields decline significantly during successive periods of stress.
Hailong Qiu, Chao Sun, Richard Dormatey, Jiangping Bai, Zhenzhen Bi, Yuhui Liu, Zhen Liu, Jingui Wei, Shoufa Mao, Panfeng Yao   +9 more
doaj   +1 more source

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Journal of Ayurveda and Integrative Medicine, 2010
Triphala (TP) is composed of Emblica officinalis, Terminalia chebula, and Terminalia belerica. The present study was undertaken to evaluate its anticataract potential in vitro and in vivo in a selenite-induced experimental model of cataract.
Suresh Kumar Gupta, V Kalaiselvan, Sushma Srivastava, Shyam S Agrawal, Rohit Saxena   +4 more
doaj   +1 more source

Serum Malondialdehyde Concentration in Babies with Hyperbilirubinaemia

, 1999
Aim-To determine lipid peroxide concentrations in the first 10 days of life. Methods-Malondialdehyde concentrations were investigated in neonates with or without hyperbilirubinaemia during the first 10 days of life.
Oran, O, Kilinc, K, Yurdakok, M, Yigit, ŞULE, Erdem, G, Yigit, S, Yurdakok, MURAT, Tekinalp, G   +7 more
core   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Malondialdehyde Level in the Cord Blood of Newborn Infants [PDF]

, 2013
Objective: In this study, we aim to demonstrate that measurement of the malondialdehyde (MDA) level in the umbilical cord blood of newborn infants born via cesarean section (C/S) and normal vaginal delivery (NVD) is indicative of oxidative stress ...
Hatipoglu, Sami, Gülbayzar, Sayat, Arica, Seçil, Kaya, Aysem, Karatekin, Güner, Arica, Vefik   +5 more
core   +2 more sources

ANALYSIS OF MALONDIALDEHYDE LEVELS IN CHILDREN WITH BETA THALASSEMIA: A CROSS-SECTIONAL STUDY [PDF]

, 2023
Beta thalassemia is an autosomal recessive genetic condition affecting people worldwide, including in Indonesia. Malondialdehyde levels, a peroxidation product, can be used to see if there is an iron buildup in the body due to lifelong transfusions. This
Alaydrus, Syarifah Raehana Mardiah, Satriono, Kwari Januar, L, Amiruddin, Alasiry, Ema, Ridha, Nadirah Rasyid, Angriani, Hadia   +5 more
core   +2 more sources