Results 41 to 50 of about 180,373 (302)

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Comprehensive Assessment of Alfalfa Aluminum Stress Resistance Using Growth and Physiological Trait Analysis

Agriculture
Alfalfa (Medicago sativa L.) is an important perennial leguminous forage; however, its high sensitivity to aluminum (Al) stress severely restricts its cultivation in regions with acidic soil. Therefore, this study conducted an integrated assessment of Al
Nannan Tang, Xiangming Zeng, Jizhi Wei, Zhou Li, Xuechun Zhao, Jihui Chen, Xinyao Gu, Chao Chen, Rui Dong   +8 more
doaj   +1 more source

Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments

Bezmiâlem Science, 2016
Objective:This study was conducted to investigate the effects of ionizing radiation (IR) and non-ionizing radiation (NIR) on oxidative stress and the total antioxidant status (TAS) in men working in radiation environments.Methods:The serum values of ...
Hakim ÇELİK, İsmail KOYUNCU, Ali Ziya KARAKILÇIK, Ataman GÖNEL, Davud MUSA   +4 more
doaj   +1 more source

Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study

Chinese Journal of Physiology, 2021
This study aimed to assess the effect of Vitamin C on blood pressure (BP), and subsequently on oxidative stress and nitric oxide (NO) release, following the low-intensity exercise in the patients.
Chongchira Boonthongkaew, Terdthai Tong-Un, Yupaporn Kanpetta, Nisa Chaungchot, Chanvit Leelayuwat, Naruemon Leelayuwat   +5 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients

Iranian Journal of Public Health, 2006
Oxidative stress arises when there is an imbalance between reactive oxygen species (ROSs) and scavenging capacity of antioxidants, and it can induce and progress many diseases such as breast cancer.
T Aghvami, M Djalali, A Keshavarz, MR Sadeghi, H Zeraati, H Sadrzadeh Yeganeh, M Negahdar   +6 more
doaj  

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Effect of lupeol on testicular lesions induced by cadmium chloride in rats [PDF]

Avicenna Journal of Phytomedicine
Objective: Heavy metals and environmental pollutants, such as cadmium chloride, congenital disorders, and certain diseases, can lead to infertility in men.
Parmida Arabkarami, Pejman Mortazavi, Saeed Hesaraki   +2 more
doaj   +1 more source

Malondialdehyde content.

, 2014
Malondialdehyde (MDA) content (nmol/g) in (A) liver and (B) gills of rainbow trout, common carp and goldfish during 1 mM ammonia exposure. Values are mean ± S.E.
Han Asard (55370), Gudrun De Boeck (553220), Hamada AbdElgawad (543144), Terri Giblen (553218), Amit Kumar Sinha (553217), Gaurav Zinta (543146), Michelle De Rop (553219), Ronny Blust (61165)   +7 more
core   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source