Results 291 to 300 of about 207,268 (343)

Probiotic supplementation and postoperative antioxidant response in patients undergoing open‑heart surgery: a randomized controlled trial. [PDF]

Cardiovasc Endocrinol Metab
Mofidi F, Kavand S, Doaei S, Shahrabi M, Javid Z, Norouzi M, Taghavi M, Dabbagh A, Fathi M, Shadnoush M.   +9 more
europepmc   +1 more source

Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu, Chuang Liu, Ya‐Li Chen, Jie‐Lin Qin, Ting‐Ting Wang, Shan‐Shan Fu   +5 more
wiley   +1 more source

Oxidative stress and cognitive function in Chinese patients with major depressive disorder: the mediating role of depression severity. [PDF]

BMC Psychiatry
Peng RJ, Sun C, Fan Y, Li J, Gao J, Sun WX, Zhang XB, Tian Q.   +7 more
europepmc   +1 more source

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu, Jing‐Wen Hou, Zhong‐Ying Lv, Ming‐Hui Sun, Xiao‐Yang Zhang, Lei Zhang, Mei Wang   +6 more
wiley   +1 more source

The interplay of tumor suppressor p53 and oxidative stress in pancreatic β-cell apoptosis and insulin resistance in newly diagnosed type 2 diabetes mellitus. [PDF]

Diabetol Metab Syndr
Al-Baqeri A, Al-Habori M, Al-Eryani E, Saif-Ali R.   +3 more
europepmc   +1 more source

CONTRIBUTION DES RESEAUX DE NEURONES ARTIFICIELS (RNA) A LA CARACTERISATION D’UN STRESS OXYDATIF CHEZ Saccharomyces cerevisiae INDUIT PAR LE CADMIUM. MISE EN EVIDENCE D’UN BIOMARQUEUR POTENTIEL (CAS DU MALONDIALDEHYDE)

, 2011
Mohamed Djekoun, R Djebar, Samira Bensoltane, Lassaad Ghrieb   +3 more
openalex   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Protective effect of adenosine triphosphate against hydroxychloroquine ototoxicity in rats. [PDF]

Sci Rep
Erhan E, Suleyman Z, Altuner D, Demir O, Gulaboglu M, Suleyman H.   +5 more
europepmc   +1 more source

Sacubitril/Valsartan Ameliorates Inflammation and Oxidative Stress in Hypertensive Heart Disease by Upregulating CAMKK2 Protein and Modulating the AMPK/AKT/GSK‐3β Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley   +1 more source