Results 101 to 110 of about 82,272 (242)

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A‐Dependent Upregulation and a FURIN‐Dependent Cleavage of the ANGPTL4 Secreted Factor

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
This article supports that ANGPTL4 secreted factor is induced transcriptionally and activated by proteolytic cleavage during senescence, contributing to the production of a pro‐inflammatory SASP. In the senescent cell microenvironment, ANGPTL4 could thus contribute to senescence‐dependent alterations such as inflammation and tumor initiation.
Gabriela Makulyte   +20 more
wiley   +1 more source

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

open access: yesPLoS Biology, 2015
During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell.
David Gallego-Ortega   +30 more
doaj   +1 more source

Development of the neurohypophysis: A major neuroendocrine interface

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis.
Athul R. Ramesh   +5 more
wiley   +1 more source

Innovative Chorioallantoic Membrane Model as Valuable Tool in Diagnostics and Testing of Domestic Animal Cancers

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
In recent years, particular attention has been paid to the possible connections, similarities, and potential uses of animals, especially pets (dogs and cats), in research on the causes, characteristics, and treatment of cancers occurring in pets and humans. One of the most promising experimental research models used to explore these issues is the avian
Anna Sczasny   +3 more
wiley   +1 more source

The Role of Oncogenic Viruses in the Pathogenesis of Sporadic Breast Cancer: A Comprehensive Review of the Current Literature

open access: yesPathogens
Breast cancer is the most common malignancy in the female sex; although recent therapies have significantly changed the natural history of this cancer, it remains a significant challenge.
Chiara Rossi   +7 more
doaj   +1 more source

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