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STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts. [PDF]
Dennaoui R +10 more
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Superantigens of Mouse Mammary Tumor Virus
Annual Review of Immunology, 1995Superantigens (SAgs) are proteins of microbial origin that bind to major histocompatibility complex (MHC) class II molecules and stimulate T cells via interaction with the V beta domain of the T cell receptor (TCR). Mouse mammary tumor virus (MMTV) is a milk-transmitted type B retrovirus that encodes a SAg in its 3' long terminal repeat.
H, Acha-Orbea, H R, MacDonald
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Surface structure of mouse mammary tumor virus
Virology, 1974Abstract The structure of the envelope of mouse mammary tumor virus (MuMTV) was studied by using negative stain, thin sections and freeze-drying-shadowing. The surface of the viral membrane was found to contain a reticular structure composed mainly of hexagons and occasional pentagons. The spacing between the nearest corners was about 74 A. The viral
Sarkar, N H, Moore, D H
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Biology of mouse mammary tumor virus (MMTV)
Cancer Letters, 1995Mouse mammary tumor viruses (MMTV) replicate in the mammary gland, appear as infectious particles in mother's milk and invade the sucking pups from the intestinal tract. The immune system is essential for MMTV in the gut to reach the mammary gland. These properties make the life cycle of MMTV unique.
A, Matsuzawa +3 more
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Identification of mouse mammary tumor virus-specific mRNA
Journal of Virology, 1979Complementary DNA corresponding to the RNA genome of mouse mammary tumor virus was used to identify viral RNA contained in polysomes of a virus-producing mammary tumor cell line. Separation of polysomal mRNA by agarose gel electrophoresis, transfer of the RNA to diazobenzyloxymethyl paper, and hybridization with 32P-labeled mouse mammary tumor virus ...
Groner, B, Hynes, N E, Diggelmann, H
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Breast Cancer and Mouse Mammary Tumor Virus
Annals of Internal Medicine, 1983Excerpt To the editor: The recent report by Poon and associates (1) provides additional evidence associating antigens of mouse mammary tumor virus with human breast cancer.
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The polypeptide composition of mouse mammary tumor virus
Virology, 1974Abstract The polypeptide composition of mouse mammary tumor virus isolated from several strains of mice, has been examined by polyacrylamide gel electrophoresis. Gel Patterns, as revealed by staining and 14 C amino acid labelling, showed 10 polypeptide species reproducibly associated with the virus.
C, Dickson, J J, Skehel
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Sandwich enzyme immunoassay of mouse mammary tumor virus
Experientia, 1981A highly sensitive sandwich enzyme immunoassay for the mouse mammary tumor virus (MMTV) is described. The assay can detect 3 ng/ml of MMTV. The enzyme used is s-D-galactosidase fromEscherichia coli and the solid phase used is a piece of silicon rubber.
M, Takahashi +6 more
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International Journal of Cancer, 1980
AbstractThe expression of the mouse mammary tumor virus (MMTV) in hormone‐induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinity‐ and ion‐exchange chromatography columns. The purified viral proteins were electrophoretically homogeneous and retained
Nusse, R +3 more
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AbstractThe expression of the mouse mammary tumor virus (MMTV) in hormone‐induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinity‐ and ion‐exchange chromatography columns. The purified viral proteins were electrophoretically homogeneous and retained
Nusse, R +3 more
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