Results 141 to 150 of about 60,982 (185)
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Mouse mammary tumor virus and mammary tumorigenesis in wild mice
Pathology International, 1996The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV.
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Journal of Virology, 1978
The involvement of the mouse mammary tumor virus (MTV) in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains was studied by comparing the amounts of MTV RNA and MTV DNA sequences in mammary tumors and other tissues of mice with an without hormonal treatments. The following results were obtained.
Michalides, R +4 more
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The involvement of the mouse mammary tumor virus (MTV) in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains was studied by comparing the amounts of MTV RNA and MTV DNA sequences in mammary tumors and other tissues of mice with an without hormonal treatments. The following results were obtained.
Michalides, R +4 more
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Mouse Mammary Tumor Virus and the Immune System
Immunologic Research, 2003Mouse mammary tumor virus (MMTV) is a nonacute transforming retrovirus that causes mammary tumors in susceptible strains of mice. Upon milk-borne transmission, B cells in the gut become infected and subsequently present a virus-encoded superantigen to cognate T cells.
Jennifer, Czarneski +2 more
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Immune response to mouse mammary tumor virus
Current Opinion in Immunology, 1996Superantigens of mouse mammary tumor virus induce a strong cognate interaction between T cells and B cells. In addition to amplifying the virus-infected B-cell pool, this superantigen-driven interaction leads to the differentiation of virus-specific B cells into plasma cells. Successful interaction between T cells and B cells is required for completion
S A, Luther, H, Acha-Orbea
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Selective amplification of mouse mammary tumor virus in mammary tumors of GR mice
Journal of Virology, 1980DNAs extracted from the mammary tumors of GR mice were analyzed for mouse mammary tumor virus proviral sequences by the restriction enzyme-Southern blot procedure. The tumor DNAs contain more proviral copies of mouse mammary tumor virus than DNA from a nonmalignant tissue. The degree of proviral amplification is small (ca. one to five additional copies)
T G, Fanning, J P, Puma, R D, Cardiff
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Molecular Aspects of Mouse Mammary Tumor Virus Biology
1987Publisher Summary This chapter outlines the structure and replication of the mouse mammary tumor virus (MMTV), and elaborates those aspects of MMTV molecular biology that have provided an insight into the understanding of gene regulation and virally induced carcinogenesis.
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Mouse Mammary Tumor Virus and Cancer
2011The retrovirus mouse mammary tumor virus (MMTV) was discovered in the 1930s as a milk-transmitted agent that causes breast cancer in mice. MMTV causes mammary tumors by insertional activation or mutation of cellular oncogenes. Some of the oncogenes activated by MMTV insertion have been also associated with human breast cancer.
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
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Mouse Mammary Tumor Virus Expression and Mammary Tumor Development
1983R, Michalides, A, van Ooyen, R, Nusse
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