Results 91 to 100 of about 44,027 (268)

Herpes simplex encephalitis in adult patients with MASP-2 deficiency.

open access: yesPLoS Pathogens, 2019
We report here two cases of Herpes simplex virus encephalitis (HSE) in adult patients with very rare, previously uncharacterized, non synonymous heterozygous G634R and R203W substitution in mannan-binding lectin serine protease 2 (MASP2), a gene encoding
Stéphanie Bibert   +13 more
doaj   +1 more source

Infusion of plasma-derived mannan-binding lectin (MBL) into MBL-deficient humans. [PDF]

open access: yes, 2003
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldOur first experience of mannan-binding lectin (MBL)-replacement therapy was with a patient experiencing recurrent erythema multiforme associated
Valdimarsson, H
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Sterile Inflammation of Brain, due to Activation of Innate Immunity, as a Culprit in Psychiatric Disorders

open access: yesFrontiers in Psychiatry, 2018
Evidence has accumulated that the occurrence of psychiatric disorders is related to chronic inflammation. In support of this linkage, changes in the levels of circulating pro-inflammatory cytokines and chemokines in the peripheral blood (PB) of ...
Mariusz Z. Ratajczak   +7 more
doaj   +1 more source

Interaction of C1q and Mannan-Binding Lectin with Viruses

open access: yesImmunobiology, 2002
As soluble recognition molecules of innate immunity, C1q and MBL are able to bind directly to various viruses, including retroviruses and influenza viruses. Interaction of C1q with retroviruses and certain infected cells was shown to involve the globular region of C1q and viral envelope glycoproteins, such as p15E of MuLV, gp41 and gp120 of HIV-1, gp21
Pascale Tacnet-Delorme   +2 more
openaire   +3 more sources

GCI‐Based Affinity Screening of Synthetic Oligomannosides toward Concanavalin A

open access: yesChemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.
This study describes the development of a reliable GCI method for the affinity determination of neo‐glycoproteins toward concanavalin A (ConA), a model lectin. The final goal is to investigate multivalent carbohydrate–lectin interactions. Abstract Herein, we report the first application of grating‐coupled interferometry (GCI) to quantify the binding ...
Davide Rubes   +9 more
wiley   +1 more source

Differential activity of a lectin from Solieria filiformis against human pathogenic bacteria

open access: yesBrazilian Journal of Medical and Biological Research, 2005
A lectin isolated from the red alga Solieria filiformis was evaluated for its effect on the growth of 8 gram-negative and 3 gram-positive bacteria cultivated in liquid medium (three independent experiments/bacterium).
M.L. Holanda   +5 more
doaj   +1 more source

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

open access: yesFrontiers in Immunology, 2022
BackgroundComplement lectin pathway components, in particular mannan-binding lectin (MBL) and MBL-associated serine proteases (MASPs) have been shown to interact with coagulation factors and contribute to clot formation.
Murielle Golomingi   +9 more
doaj   +1 more source

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]

open access: yes, 2017
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N   +5 more
core   +1 more source

Engineered Dual‐Function Antibody‐Like Proteins to Combat SARS‐CoV‐2‐Induced Immune Dysregulation and Inflammation

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang   +7 more
wiley   +1 more source

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