Results 101 to 110 of about 13,265 (210)

The Emerging Role of Complement Lectin Pathway in Trypanosomatids: Molecular Bases in Activation, Genetic Deficiencies, Susceptibility to Infection, and Complement System-Based Therapeutics

The Scientific World Journal, 2013
The innate immune system is evolutionary and ancient and is the pivotal line of the host defense system to protect against invading pathogens and abnormal self-derived components. Cellular and molecular components are involved in recognition and effector
Ingrid Evans-Osses, Iara de Messias-Reason, Marcel I. Ramirez   +2 more
doaj   +1 more source

Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer

Swiss Medical Weekly, 2011
QUESTIONS UNDER STUDY: Mannan-binding lectin (MBL) and MBL-associated serine protease-2 (MASP-2) are two key components of the lectin-pathway of complement-activation. Information on the potential role of lectin-pathway components in carcinogenesis
UP Fisch, A Hirt, A Simon, H Ozsahin, FK Niggli, LJ Schlapbach, RA Ammann   +6 more
doaj   +1 more source

Análise das variantes polimórficas do éxon 1 do gene que codifica lectina de ligação a manose (MBL2) em pacientes com artrite reumatóide [PDF]

, 2011
Rheumatoid arthritis is an autoimmune disease that operates through joint inflammation becomes chronic over the years and may develop a deformity and destruction of these joints due to erosion of cartilage and bone.
Martiny, Fernanda Letícia
core  

Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of glycoside hydrolase. [PDF]

, 2014
BackgroundGut microbiome metagenomics has revealed many protein families and domains found largely or exclusively in that environment. Proteins containing the GxGYxYP domain are over-represented in the gut microbiota, and are found in Polysaccharide ...
Chang, Yuanyuan, Eberhardt, Ruth Y, Gilbert, Harry J, Godzik, Adam, Rigden, Daniel J, Xu, Qingping   +5 more
core   +2 more sources

Chromosome‐level genome assembly of the photobiont microalga Trebouxia sp. ‘A48’ from the lichen Xanthoria parietina

New Phytologist, Volume 249, Issue 2, Page 1036-1052, January 2026.
Summary Lichens are symbiotic assemblies consisting of multiple organisms, chiefly a fungus and a photosynthetic microorganism, or photobiont. Among diverse photobionts, the most prevalent is the chlorophyte alga Trebouxia. We produced a chromosome‐level assembly of Trebouxia sp. ‘A48’, a photobiont of Xanthoria parietina. The genome was assembled into
Gulnara Tagirdzhanova, Jasper Raistrick, Nicholas J. Talbot   +2 more
wiley   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Sugary interfaces mitigate contact damage where stiff meets soft [PDF]

, 2016
The byssal threads of the fan shell Atrina pectinata are non-living functional materials intimately associated with living tissue, which provide an intriguing paradigm of bionic interface for robust load-bearing device.
A Miserez, AM Smith, AN Zelensky, B Bar-On, B Bhushan, BP Lee, C Sun, D Gourdon, DS Hwang, E Hennebert, ED Reedy Jr, EJ Evans, GL Nicolson, H Lee, H Silverman, H Zeng, H Zhao, J Israelachvili, JH Waite, JH Waite, JH Zettl, JJ Wilker, JM Mascolo, K Ohkawa, K Ono, KJ Coyne, LA Burzio, LL Hench, M Benjamin, M Wiegemann, MA Paz, MJ Harrington, MJ Harrington, MK Kwak, MS Stanley, N Bandara, N Holten-Andersen, N Poulsen, P Fratzl, S Menon, S Suresh, T Pearce, T Pearce, WC Oliver, X-X Qin, Y Zhou   +45 more
core   +3 more sources

16th IHIW: Immunogenetics of Aging [PDF]

, 2013
Ageing is a process characterised by progressive loss of function in multiple different organ systems, such as the nervous, endocrine and immune systems.
Bogunia Kubik, K, CARUSO, Calogero, Constantinescu, I, Franceschi, C, Ivanova, M, Lange, A, Middleton, D., Mishra, M, Naumova, E, Oguz, F, Ozdilli, K, Pawelec, G   +11 more
core   +1 more source

Mannose/mannan-binding lectin

, 2013
Mannose/mannan-binding lectin (MBL) is a serum lectin synthesized (as a ~32 kDa peptide) by the liver and is one of the key molecules of the innate immune system. Each peptide has an N (amino)-terminal cysteine-rich region, a middle stretch of a collagen-like sequence, and a carbohydrate recognition domain (CRD) in the C (carboxy)-terminus.
Dinasarapu, Ashok Reddy, Chandrasekhar, Anjana, Fujita, Teizo, Subramaniam, Shankar   +3 more
openaire   +1 more source

Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.

PLoS ONE, 2007
The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. The lectin pathway is one pathway of three by which the complement system is activated.
Anders Krarup, Russell Wallis, Julia S Presanis, Péter Gál, Robert B Sim   +4 more
doaj   +1 more source