Results 111 to 120 of about 44,027 (268)

Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli

ChemBioChem, Volume 26, Issue 17, September 15, 2025.
This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa, Shane M. Coyle, Fiona Walsh, Trinidad Velasco‐Torrijos   +3 more
wiley   +1 more source

Soluble Host Defense Lectins in Innate Immunity to Influenza Virus [PDF]

, 2012
Host defenses against viral infections depend on a complex interplay of innate (nonspecific) and adaptive (specific) components. In the early stages of infection, innate mechanisms represent the main line of host defense, acting to limit the spread of ...
Andrew G. Brooks, Michelle D. Tate, Patrick C. Reading, Wy Ching Ng   +3 more
core   +2 more sources

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae [PDF]

, 2017
The human fungal microbiota known as mycobiota is increasingly recognized as a critical factor in human gut health and disease. Non-pathogenic commensal yeasts such as Saccharomyces cerevisiae promote homeostasis in the gut, whereas dysbiosis of the gut ...
Brown, Cadwell, Cambi, Chu, Cuskin, Delgado, Dooley Hannah, Feinberg, Hall, Ifrim, Iliev, Joffe, Kanayama, Kelesidis, Kohatsu, Laroux, Li, Ma, Macauley, Martinez, Martinez, Martinez, McGreal, Netea, Robinson, Saijo, Salehi, Sanjuan, Sato, Sokol, Tam, Underhill, van Kooyk, Viriyakosol, Wagener, Wang, Wells, West, Wex, Wheeler, Wirnsberger, Wittmann, Yonekawa, Yuan, Zhu   +44 more
core   +2 more sources

The Etiopathogenesis of Kawasaki Disease: Evolving Understanding of Diverse Triggers

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
ABSTRACT Background Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Evidence suggests that microbial and nonmicrobial triggers for KD differ across geographical regions and environmental conditions. Although the precise triggers remain unidentified, KD is likely caused by microbial or environmental agents acting on ...
Toshiro Hara, Yasunari Sakai
wiley   +1 more source

Scabies mite peritrophins are potential targets of human host innate immunity. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Pruritic scabies lesions caused by Sarcoptes scabiei burrowing in the stratum corneum of human skin facilitate opportunistic bacterial infections.
Angela Mika, Priscilla Goh, Deborah C Holt, Dave J Kemp, Katja Fischer   +4 more
doaj   +1 more source

Chimerolectins: Classification, structural architecture, and functional perspectives

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior, Benildo Sousa Cavada, Kyria Santiago Nascimento   +2 more
wiley   +1 more source

The pandemic (H1N1) 2009 influenza virus is resistant to mannose-binding lectin

Virology Journal, 2011
Background Mannose-binding lectin (MBL) is an important component of innate immunity because it promotes bacterial clearance and neutralization of human influenza A viruses.
Ushirogawa Hiroshi, Tokunaga Hirotoshi, Ohuchi Masanobu   +2 more
doaj   +1 more source

Immunity against fungal beta 1,3 glucan carbohydrate in the gastrointestinal tract [PDF]

, 2016
Inflammatory Bowel Disease (IBD) is a debilitating, life- long disease that affects about 1.4 millions Americans. Little is known about the pathogenesis of IBD and an effective cure still remains to be discovered.
Feliu, Marianela
core   +1 more source

Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation cascades

Leukemia, 2016
Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation ...
M. Adamiak, Ahmed Abdelbaset-Ismail, M. Suszyńska, A. Abdel-Latif, J. Ratajczak, M. Ratajczak   +5 more
semanticscholar   +1 more source