Role of mannose-binding lectin in the innate defense against Candida albicans: Enhancement of complement activation, but lack of opsonic function, in phagocytosis by human dendritic cells [PDF]
Mannose-binding lectin (MBL) is a serum collectin believed to be of importance in innate immunity. We have investigated the role of MBL in the first-line defense against Candida albicans, an opportunistic fungal pathogen. MBL bound C.
Ip, WK, Lau, YL
core +1 more source
Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes. [PDF]
Lymphocyte migration from the blood into most secondary lymphoid organs is initiated by a highly selective adhesive interaction with the endothelium of specialized blood vessels known as high endothelial venules (HEV).
Geoffroy, JS, Rosen, SD
core
Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes. [PDF]
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Arnardottir, Margret +2 more
core +1 more source
Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important Innate Immune Response Genes [PDF]
Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma.
Bronkhorst, M.W.G.A. (Maarten) +2 more
core +2 more sources
New perspectives on mannan-binding lectin-mediated complement activation
The complement system is an important part of the innate immune system, mediating several major effector functions and modulating adaptive immune responses. Three complement activation pathways exist: the classical pathway (CP), the alternative pathway (AP), and the lectin pathway (LP).
Degn, Søren Egedal +2 more
openaire +3 more sources
The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis
Innate immunity plays an important role in orchestrating the immune response, and the complement cascade (ComC) is a major component of this ancient defense system, which is activated by the classical-, alternative-, or mannan-binding lectin (MBL ...
Mariusz Z. Ratajczak +7 more
doaj +1 more source
Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women. [PDF]
Gao M +12 more
europepmc +1 more source
A likely association between low mannan-binding lectin level and brain fog onset in long COVID patients. [PDF]
Bulla R +10 more
europepmc +1 more source
A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin. [PDF]
Iqbal H +6 more
europepmc +1 more source
Mannan-Binding Lectin Promotes Murine Graft-versus-Host Disease by Amplifying Lipopolysaccharide-Initiated Inflammation. [PDF]
Heja D +10 more
europepmc +1 more source

