Results 121 to 130 of about 44,027 (268)

A Structural Bridge Between Kingdoms: How Collagen‐Derived Peptides Influence Plant Stress and Growth Pathways

Physiologia Plantarum, Volume 177, Issue 5, September/October 2025.
ABSTRACT Collagen‐derived protein hydrolysates (CDPH) are widely used as plant biostimulants primarily due to their content of bioactive oligopeptides. When applied to hydroponically grown Solanum lycopersicum plants, CDPH significantly promoted root development, particularly by increasing the number and length of lateral roots.
Stefano Ambrosini, Alejandro Giorgetti, Marika Peli, Tiziana Pandolfini, Anita Zamboni, Zeno Varanini   +5 more
wiley   +1 more source

Inherited deficiency of the initiator molecules of the lectin-complement pathway [PDF]

, 2010
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization.
Björn Rúnar Lúðvíksson, Helga Bjarnadóttir   +1 more
core  

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

Advanced Science, Volume 12, Issue 32, August 28, 2025.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen, Wei Bao, Kaiyuan Liu, Na Jing, Genyu Du, Luyao Jiang, Qian You, Yingchao Zhang, Penghui Xu, Chaping Cheng, Nan Wang, Xialian Xi, Mingyue Wang, Yiyun Liu, Jinming Wang, Huifang Zhao, Shilei Zhang, Dinglan Wu, Chi‐Fai Ng, Jiahua Pan, Wei Xue, Wei‐Qiang Gao, Pengcheng Zhang, Kai Zhang, Helen He Zhu   +24 more
wiley   +1 more source

GMP‐Compliant Process for the Manufacturing of an Extracellular Vesicles‐Enriched Secretome Product Derived From Cardiovascular Progenitor Cells Suitable for a Phase I Clinical Trial

Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.
ABSTRACT Extracellular vesicle (EV)‐enriched secretomes are emerging as a new and innovative therapeutic option in the field of regenerative medicine. The clinical use of EV‐enriched secretome‐based products requires manufacturing processes and quality control (QC) testing that comply with current good manufacturing practice (GMP).
Camille Humbert, Chloé Cordier, Iouri Drut, Michele Hamrick, Jacquelyn Wong, Valérie Bellamy, Justine Flaire, Kiranmayee Bakshy, Florent Dingli, Damarys Loew, Jérôme Larghero, Jean‐Roch Fabreguettes, Philippe Menasché, Nisa K. Renault, Guillaume Churlaud   +14 more
wiley   +1 more source

High production MBL2 polymorphisms protect against COVID-19 complications in critically ill patients: A retrospective cohort study

Heliyon
Mannose-binding lectin (MBL) binds to SARS-CoV-2, inhibits infection of susceptible cells, and activates the complement system via the lectin pathway. In this study, we investigated the association of MBL2 polymorphisms with the risk of hospitalization ...
Lorena Viana de Andrade, Mirela Vanessa de Souza Sá, Beatriz Vasconcelos, Luydson Richardson Silva Vasconcelos, Ricardo Khouri, Carlos Dornels Freire de Souza, Anderson da Costa Armstrong, Rodrigo Feliciano do Carmo   +7 more
doaj   +1 more source

MASP-2 Is a Heparin-Binding Protease; Identification of Blocking Oligosaccharides

Frontiers in Immunology, 2020
It is well-known that heparin and other glycosaminoglycans (GAGs) inhibit complement activation. It is however not known whether fractionation and/or modification of GAGs might deliver pathway-specific inhibition of the complement system.
Ditmer T. Talsma, Felix Poppelaars, Wendy Dam, Anita H. Meter-Arkema, Romain R. Vivès, Peter Gál, Geert-Jan Boons, Geert-Jan Boons, Pradeep Chopra, Annamaria Naggi, Marc A. Seelen, Stephan P. Berger, Mohamed R. Daha, Coen A. Stegeman, Jacob van den Born, the COMBAT Consortium   +15 more
doaj   +1 more source

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules. [PDF]

, 1990
The binding of lymphocytes to high endothelial venules (HEV) within peripheral lymph nodes (pln) is thought to be mediated by a lectinlike adhesion molecule termed the pln homing receptor (pln HR). The cloning and sequencing of cDNAs encoding both murine
Fennie, C, Geoffroy, JS, Imai, Y, Lasky, LA, Rosen, SD, Watson, SR   +5 more
core  

Sugary interfaces mitigate contact damage where stiff meets soft [PDF]

, 2016
The byssal threads of the fan shell Atrina pectinata are non-living functional materials intimately associated with living tissue, which provide an intriguing paradigm of bionic interface for robust load-bearing device.
A Miserez, AM Smith, AN Zelensky, B Bar-On, B Bhushan, BP Lee, C Sun, D Gourdon, DS Hwang, E Hennebert, ED Reedy Jr, EJ Evans, GL Nicolson, H Lee, H Silverman, H Zeng, H Zhao, J Israelachvili, JH Waite, JH Waite, JH Zettl, JJ Wilker, JM Mascolo, K Ohkawa, K Ono, KJ Coyne, LA Burzio, LL Hench, M Benjamin, M Wiegemann, MA Paz, MJ Harrington, MJ Harrington, MK Kwak, MS Stanley, N Bandara, N Holten-Andersen, N Poulsen, P Fratzl, S Menon, S Suresh, T Pearce, T Pearce, WC Oliver, X-X Qin, Y Zhou   +45 more
core   +3 more sources

Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
Polymicrobial biofilms: interkingdom interactions, resistance and therapeutic stratergies. This review highlights the heightened drug resistance and complexity of polymicrobial biofilms, emphasising their persistence over mono‐species counterparts. It explores microbial interactions, resistance mechanisms and emerging strategies, including metabolite ...
Paramasivam Nithyanand, Bharath Reddy Boya, Jin‐Hyung Lee, Jintae Lee   +3 more
wiley   +1 more source

The Emerging Role of Complement Lectin Pathway in Trypanosomatids: Molecular Bases in Activation, Genetic Deficiencies, Susceptibility to Infection, and Complement System-Based Therapeutics

The Scientific World Journal, 2013
The innate immune system is evolutionary and ancient and is the pivotal line of the host defense system to protect against invading pathogens and abnormal self-derived components. Cellular and molecular components are involved in recognition and effector
Ingrid Evans-Osses, Iara de Messias-Reason, Marcel I. Ramirez   +2 more
doaj   +1 more source